Mutations in the deubiquitinase gene USP8 cause Cushing's disease (Q41716700)

7 October 2017

title

Mutations in the deubiquitinase gene USP8 cause Cushing's disease (English)

1 reference

7 October 2017

6

1 reference

7 October 2017

7

1 reference

7 October 2017

15

1 reference

7 October 2017

Marily Theodoropoulou

4

object named as

Marily Theodoropoulou

1 reference

7 October 2017

Kohei Kawaguchi

9

0 references

Silviu Sbiera

object named as

Silviu Sbiera

2

0 references

Martin Fassnacht

19

object named as

Martin Fassnacht

1 reference

7 October 2017

12

Thomas Wieland

1 reference

7 October 2017

1

Martin Reincke

1 reference

7 October 2017

18

Tim M Strom

1 reference

7 October 2017

16

Bruno Allolio

1 reference

7 October 2017

17

Michael Buchfelder

1 reference

7 October 2017

14

Wolfgang Saeger

1 reference

7 October 2017

Akira Hayakawa

3

1 reference

7 October 2017

Andrea Osswald

5

1 reference

7 October 2017

Emi Mizuno-Yamasaki

8

1 reference

7 October 2017

Yasushi Saeki

10

1 reference

7 October 2017

Keiji Tanaka

11

1 reference

7 October 2017

Elisabeth Graf

13

1 reference

7 October 2017

Masayuki Komada

20

1 reference

7 October 2017

language of work or name

English

0 references

publication date

8 December 2014

1 reference

7 October 2017

1 reference

7 October 2017

volume

47

1 reference

7 October 2017

issue

1

1 reference

7 October 2017

page(s)

31-38

1 reference

The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes.

7 October 2017

cites work

1 reference

The molecular pathogenesis of corticotroph tumours

21 January 2018

1 reference

Expression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells.

21 January 2018

1 reference

EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas

21 January 2018

1 reference

Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome

21 January 2018

1 reference

Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome

21 January 2018

1 reference

Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors

21 January 2018

1 reference

Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome.

21 January 2018

1 reference

Prediction of the Coding Sequences of Unidentified Human Genes. II. The Coding Sequences of 40 New Genes (KIAA0041-KIAA0080) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

21 January 2018

1 reference

The ubiquitin-proteasome proteolytic pathway

21 January 2018

1 reference

Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

21 January 2018

1 reference

Governance of endocytic trafficking and signaling by reversible ubiquitylation

21 January 2018

1 reference

The role of ubiquitylation in receptor endocytosis and endosomal sorting

21 January 2018

1 reference

The ubiquitin code and its decoding machinery in the endocytic pathway

21 January 2018

1 reference

Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

21 January 2018

1 reference

Breaking the chains: structure and function of the deubiquitinases

21 January 2018

1 reference

Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes

21 January 2018

1 reference

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

21 January 2018

1 reference

A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes

21 January 2018

1 reference

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

21 January 2018

1 reference

UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradation

21 January 2018

1 reference

Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo

21 January 2018

1 reference

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

21 January 2018

1 reference

14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.

21 January 2018

1 reference

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

21 January 2018

1 reference

Orchestration of cell surface proteins by Rab11.

21 January 2018

1 reference

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

21 January 2018

1 reference

Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells

21 January 2018

1 reference

A role for Hrs in endosomal sorting of ligand-stimulated and unstimulated epidermal growth factor receptor

21 January 2018

1 reference

Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes

21 January 2018

1 reference

Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice

21 January 2018

1 reference

Ketoconazole inhibits corticotropic cell function in vitro

21 January 2018

1 reference

A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP

21 January 2018

1 reference

DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy

21 January 2018

1 reference

Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes

21 January 2018

1 reference

Pathogenesis of pituitary tumors

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Retinoic acid prevents experimental Cushing syndrome

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.3166

1 reference

Dimensions Publication ID

7 October 2017

1027553209

0 references

1 reference