A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer (Q41716703)

7 October 2017

title

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer (English)

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7 October 2017

36

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37

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7 October 2017

Maren Hieber

10

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Katja Steiger

Katja Steiger

8

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Ignacio Varela

Ignacio Varela

20

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George S Vassiliou

George Vassiliou

41

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Mathias Heikenwälder

27

Mathias Heikenwälder

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7 October 2017

40

Michael A Quail

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42

Irene Esposito

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Roland Rad

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Lena Rad

2

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7 October 2017

Wei Wang

3

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7 October 2017

Alexander Strong

4

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Hannes Ponstingl

5

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Iraad F Bronner

6

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Matthew Mayho

7

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Julia Weber

9

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Christian Veltkamp

11

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Stefan Eser

12

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Ulf Geumann

13

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Rupert Öllinger

14

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Magdalena Zukowska

15

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Maxim Barenboim

16

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Roman Maresch

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Juan Cadiñanos

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Mathias Friedrich

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Fernando Constantino-Casas

21

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Aaron Sarver

22

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Jelle Ten Hoeve

23

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Haydn Prosser

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Barbara Seidler

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Judith Bauer

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Emmanouil Metzakopian

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Anne Krug

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Ursula Ehmer

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Günter Schneider

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Thomas Knösel

32

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Petra Rümmele

33

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Daniela Aust

34

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Robert Grützmann

35

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Lodewyk Wessels

38

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Roland M Schmid

39

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7 October 2017

Pentao Liu

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Dieter Saur

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7 October 2017

Allan Bradley

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7 October 2017

language of work or name

English

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publication date

8 December 2014

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7 October 2017

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7 October 2017

volume

47

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7 October 2017

issue

1

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7 October 2017

page(s)

47-56

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Hallmarks of Cancer: The Next Generation

7 October 2017

cites work

1 reference

The art and design of genetic screens: Drosophila melanogaster

21 January 2018

1 reference

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

21 January 2018

1 reference

Transposon-mediated genome manipulation in vertebrates

21 January 2018

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Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

21 January 2018

1 reference

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

21 January 2018

1 reference

Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.

21 January 2018

1 reference

Regulated transposition of a fish transposon in the mouse germ line

21 January 2018

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Transposition and gene disruption in the male germline of the mouse

21 January 2018

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Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.

21 January 2018

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Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

21 January 2018

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A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

21 January 2018

1 reference

A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

21 January 2018

1 reference

A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice

21 January 2018

1 reference

Harnessing transposons for cancer gene discovery

21 January 2018

1 reference

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice

21 January 2018

1 reference

Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons.

21 January 2018

1 reference

Chromosomal transposition of PiggyBac in mouse embryonic stem cells

21 January 2018

1 reference

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

21 January 2018

1 reference

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

21 January 2018

1 reference

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

21 January 2018

1 reference

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

21 January 2018

1 reference

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

21 January 2018

1 reference

TAPDANCE: an automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data

21 January 2018

1 reference

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

21 January 2018

1 reference

FOXP1: a potential therapeutic target in cancer.

21 January 2018

1 reference

The landscape of somatic copy-number alteration across human cancers

21 January 2018

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

21 January 2018

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A map of the cis-regulatory sequences in the mouse genome

21 January 2018

1 reference

The accessible chromatin landscape of the human genome

21 January 2018

1 reference

Genetics of coronary artery disease.

21 January 2018

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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

21 January 2018

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Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

21 January 2018

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A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling

21 January 2018

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Roles of BCL6 in normal and transformed germinal center B cells

21 January 2018

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Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes

21 January 2018

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Hepatoid adenocarcinoma - review of the literature illustrated by a rare case originating in the peritoneal cavity

21 January 2018

1 reference

AAA+ proteins: have engine, will work

21 January 2018

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The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development

21 January 2018

1 reference

Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis

21 January 2018

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Characterization of enhancer function from genome-wide analyses

21 January 2018

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Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells

21 January 2018

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Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas

21 January 2018

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Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

21 January 2018

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Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

21 January 2018

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

21 January 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

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Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice

21 January 2018

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CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer

21 January 2018

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CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo.

21 January 2018

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Transposons in C. elegans

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.3164

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Dimensions Publication ID

7 October 2017

1009339870

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