Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells (Q41724208)

8 October 2017

Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells (English)

1 reference

8 October 2017

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1698059

1 November 2022

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https://api.crossref.org/works/10.1042/BJ2700383

1 November 2022

1 reference

https://api.crossref.org/works/10.1042/BJ2700383

1 November 2022

author name string

M. A. Soos

1

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1 November 2022

J. Whittaker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1698059

1 November 2022

R. Lammers

3

1 reference

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1 November 2022

A. Ullrich

4

1 reference

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1 November 2022

K. Siddle

5

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1 November 2022

language of work or name

English

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publication date

1 September 1990

1 reference

PMCID

1131733

full work available at URL

8 October 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1698059/pdf/?tool=EBI

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1698059

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1698059/?tool=EBI

1 November 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1698059

https://europepmc.org/articles/PMC1131733

1 November 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1698059

https://europepmc.org/articles/PMC1131733?pdf=render

1 November 2022

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Portable Document Format

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open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1698059

https://portlandpress.com/biochemj/article-pdf/270/2/383/600924/bj2700383.pdf

1 November 2022

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Portable Document Format

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https://api.crossref.org/works/10.1042/BJ2700383

1 November 2022

1 reference

8 October 2017

270

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8 October 2017

2

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8 October 2017

383-390

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1 Preparation of monoclonal antibodies: Strategies and procedures

8 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Tyrosine A14[125I]monoiodoinsulin: Preparation, Biologic Properties, and long-term stability

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The insulin receptor. Structural basis for high affinity ligand binding

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

High-level expression of human insulin receptor cDNA in mouse NIH 3T3 cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Growth factor receptor tyrosine kinases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

An atypical insulin receptor with high affinity for insulin-like growth factors copurified with placental insulin receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Actions of insulin-like growth factors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The nature and regulation of the receptors for insulin-like growth factors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The nature and regulation of the insulin receptor: structure and function

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The structural basis for insulin-like growth factor I receptor high affinity binding

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Expression and characterization of a functional human insulin-like growth factor I receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Comparison of insulin and insulin-like growth factor I receptors from rat skeletal muscle and L-6 myocytes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The metabolic and mitogenic effects of both insulin and insulin-like growth factor are enhanced by transfection of insulin receptors into NIH3T3 fibroblasts.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

A novel fetal insulin-like growth factor (IGF) I receptor. Mechanism for increased IGF I- and insulin-stimulated tyrosine kinase activity in fetal muscle

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

The insulin receptor: structure and function

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Delineation of atypical insulin receptors from classical insulin and type I insulin-like growth factor receptors in human placenta

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

IGF-II binding on human lymphoid cells: Demonstration of a common high affinity receptor for insulin like peptides

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

Monoclonal antibodies to receptors for insulin and somatomedin-C

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131733

16 Methods for assessing immunologic and biologic properties of iodinated peptide hormones

18 August 2018

1 reference

12 December 2020

Relationship between insulin receptor subunit association and protein kinase activation: insulin-dependent covalent and Mn/MgATP-dependent noncovalent association of alpha beta heterodimeric insulin receptors into an alpha 2 beta 2 heterotetrameric

1 reference

12 December 2020

Insulin-like growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers

1 reference

12 December 2020

Assembly of insulin/insulin-like growth factor-1 hybrid receptors in vitro

1 reference

12 December 2020

Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell

1 reference

12 December 2020

Isolation of functional alpha beta heterodimers from the purified human placental alpha 2 beta 2 heterotetrameric insulin receptor complex. A structural basis for insulin binding heterogeneity

1 reference

12 December 2020

Anomalous insulin-binding activity in the bovine neural retina: a possible mechanism for regulation of receptor binding specificity

1 reference

12 December 2020

Structural and immunological characterization of insulin-like growth factor II binding to IM-9 cells

1 reference

12 December 2020

Insulin-like growth factor I rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells

1 reference

12 December 2020

Separation and characterization of three insulin receptor species that differ in subunit composition

1 reference

12 December 2020

Insulin-dependent covalent reassociation of isolated alpha beta heterodimeric insulin receptors into an alpha 2 beta 2 heterotetrameric disulfide-linked complex

1 reference

12 December 2020

One-step purification of mouse monoclonal antibodies from ascites fluid by hydroxylapatite chromatography

1 reference

12 December 2020

Evidence that insulin receptor from human placenta has a high affinity for only one molecule of insulin

1 reference

12 December 2020

Functional properties of an isolated alpha beta heterodimeric human placenta insulin-like growth factor 1 receptor complex

1 reference

12 December 2020

Characterization of two insulin-binding components of rat-liver plasma membranes

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2700383

1 reference

8 October 2017

1 reference

8 October 2017

1 reference

PMCID

1131733