Control of pRB phosphorylation (Q41732727)

8 October 2017

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title

Control of pRB phosphorylation (English)

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8 October 2017

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Mittnacht S

1

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8 October 2017

1 February 1998

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Current Opinion in Genetics & Development

8 October 2017

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8 October 2017

8

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8 October 2017

1

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8 October 2017

21-27

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The retinoblastoma protein pathway and the restriction point

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cell cycle and cancer: critical events at the G1 restriction point.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Transcriptional control of the cell cycle

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Modulation of retinoblastoma protein activity during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

High molecular weight protein phosphatase type 1 dephosphorylates the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Phosphorylation of protein phosphatase-1 isoforms by cdc2-cyclin B in vitro

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Constitutively active protein phosphatase 1alpha causes Rb-dependent G1 arrest in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Control and activity of type-1 serine/threonine protein phosphatase during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

p53-mediated accumulation of hypophosphorylated pRb after the G1 restriction point fails to halt cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The retinoblastoma gene product is reversibly dephosphorylated and bound in the nucleus in S and G2 phases during hypoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Late dephosphorylation of the RB protein in G2 during the process of induced cell differentiation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Mammalian antiproliferative signals and their targets.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

The role of p27Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-alpha in hematopoietic cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Signal transduction through the GTP-binding proteins Rac and Rho.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

Regulation of RNA polymerases I and III by the retinoblastoma protein: a mechanism for growth control?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980057-9

7 January 2021

10.1016/S0959-437X(98)80057-9

Identifiers

DOI

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8 October 2017

1 reference

PubMed ID

9529601