Human intestinal permeability (Q41741549)

8 October 2017

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title

Human intestinal permeability (English)

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8 October 2017

Lennernäs H

1

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PubMed ID

9548891

8 October 2017

language of work or name

English

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publication date

1 April 1998

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Journal of Pharmaceutical Sciences

8 October 2017

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8 October 2017

87

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8 October 2017

403-410

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8 October 2017

4

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Passage of molecules through the wall of the gastrointestinal tract. Urinary recovery of different-sized polyethylene glycols after intravenous and intestinal deposition

8 October 2017

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7 January 2021

Intestinal permeability: clinical correlates

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7 January 2021

Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man

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7 January 2021

Regional rectal perfusion: a new in vivo approach to study rectal drug absorption in man.

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7 January 2021

Intestinal permeability: an overview

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7 January 2021

Intestinal drug absorption during induced net water absorption in man; a mechanistic study using antipyrine, atenolol and enalaprilat

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7 January 2021

Does fluid flow across the intestinal mucosa affect quantitative oral drug absorption? Is it time for a reevaluation?

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7 January 2021

Viewpoints in intestinal permeability

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7 January 2021

Viewpoints in intestinal permeability

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7 January 2021

Cotransport of water by the Na+/glucose cotransporter

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7 January 2021

The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

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7 January 2021

How structural features influence the biomembrane permeability of peptides

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7 January 2021

Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

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7 January 2021

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

1 reference

7 January 2021

Lipophilicity in molecular modeling

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7 January 2021

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

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7 January 2021

A residence-time distribution analysis of the hydrodynamics within the intestine in man during a regional single-pass perfusion with Loc-I-Gut: in-vivo permeability estimation

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7 January 2021

Jejunal permeability and hepatic extraction of fluvastatin in humans

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7 January 2021

Analysis of models for determining intestinal wall permeabilities

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7 January 2021

Determinants of apical membrane permeabilities of barrier epithelia

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7 January 2021

The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons

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7 January 2021

Permeability and clearance views of drug absorption: a commentary

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7 January 2021

Oral absorption of peptides: the effect of absorption site and enzyme inhibition on the systemic availability of metkephamid

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7 January 2021

Rat jejunal permeability and metabolism of mu-selective tetrapeptides in gastrointestinal fluids from humans and rats

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7 January 2021

Site-dependent small intestinal absorption of ranitidine

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7 January 2021

Direct demonstration of small intestinal secretion and site-dependent absorption of the beta-blocker talinolol in humans

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7 January 2021

Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man

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7 January 2021

Effect of glycine-conjugated bile acids with and without lecithin on water and glucose absorption in perfused human jejunum

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7 January 2021

Absorption of glucose, sodium, and water by the human jejunum studied by intestinal perfusion with a proximal occluding balloon and at variable flow rates

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7 January 2021

Validation of the use of a tube with a proximal occlusive balloon for measurement of intestinal absorption in man

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7 January 2021

The effect of L-leucine on the absorption of levodopa, studied by regional jejunal perfusion in man.

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7 January 2021

Studies of the different metabolic pathways of antipyrine in man. Oral versus i.v. administration and the influence of urinary collection time

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7 January 2021

The lack of effect of induced net fluid absorption on the in vivo permeability of terbutaline in the human jejunum

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7 January 2021

Comparison between permeability coefficients in rat and human jejunum

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7 January 2021

Jejunal permeability: a comparison between the ussing chamber technique and the single-pass perfusion in humans

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7 January 2021

Bidirectional small intestinal permeability changes to different-sized molecules after HCl-induced injury in the rat

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7 January 2021

The method of intraluminal perfusion of the human small intestine. I. Principle and technique

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7 January 2021

Further studies on the perfusion method for measuring intestinal absorption in man: the effects of a proximal occlusive balloon and a mixing segment

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7 January 2021

Studies of intestinal digestion and absorption in the human

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7 January 2021

The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids

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7 January 2021

Clinical Pharmacokinetics of β-Adrenoreceptor Blocking Drugs

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7 January 2021

Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate

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7 January 2021

The jejunal secretion of histamine is increased in active Crohn's disease

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7 January 2021

Enhanced local production of complement components in the small intestines of patients with Crohn's disease

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7 January 2021

A new approach for direct in vivo dissolution studies of poorly soluble drugs

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7 January 2021

Use of carbon monoxide to measure luminal stirring in the rat gut.

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7 January 2021

Unstirred layer and kinetics of electrogenic glucose absorption in the human jejunum in situ

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7 January 2021

Drug absorption by the rat jejunum perfused in situ. Dissociation from the pH-partition theory and role of microclimate-pH and unstirred layer.

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7 January 2021

Dynamic NMR measurement of volume regulatory changes in Amphiuma RBC Na+ content.

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7 January 2021

Physiological measurements of luminal stirring in the dog and human small bowel

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7 January 2021

Role of villous surface area in absorption. Science versus religion

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7 January 2021

The contribution of solvent drag to the intestinal absorption of the basic drugs amidopyrine and antipyrine from the jejunum of the rat

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7 January 2021

Solvent drag effect in drug intestinal absorption. I. Studies on drug and D2O absorption clearances

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7 January 2021

Water and solute absorption from hypotonic glucose-electrolyte solutions in human jejunum

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7 January 2021

Mechanisms and sites of mannitol permeability of small and large intestine in the rat.

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7 January 2021

Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat

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7 January 2021

Effect of D-glucose on intestinal permeability and its passive absorption in human small intestine in vivo

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7 January 2021

Paracellular intestinal transport of six-carbon sugars is negligible in the rat

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7 January 2021

The influence of net water absorption on the permeability of antipyrine and levodopa in the human jejunum

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7 January 2021

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

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7 January 2021

Proton flux mechanisms in model and biological membranes

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7 January 2021

Guts. How to be physiological.

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7 January 2021

Physiological regulation of intestinal epithelial tight junctions as a consequence of Na(+)-coupled nutrient transport

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7 January 2021

Active transport of 3-O-methyl-glucose by the small intestine in chronically catheterized rats

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7 January 2021

Correlation of drug absorption with molecular surface properties

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7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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7 January 2021

Design of drugs involving the concepts and theories of drug metabolism and pharmacokinetics

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7 January 2021

Estimation of impurity profiles of drugs and related materials. 12. Isolation and identification of an isomeric impurity in danazol

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7 January 2021

Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion

1 reference

7 January 2021

Interpatient variability in bioavailability is related to the extent of absorption: implications for bioavailability and bioequivalence studies

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7 January 2021

Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments

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7 January 2021

Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2).

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7 January 2021

(+) and (-) terbutaline are sulphated at a higher rate in human intestine than in liver

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7 January 2021

Identifiers

DOI

10.1021/JS970332A

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8 October 2017

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PubMed ID

9548891