To what extent have functional studies of ischaemia in animals been useful in the assessment of potential neuroprotective agents? (Q41742763)

8 October 2017

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title

To what extent have functional studies of ischaemia in animals been useful in the assessment of potential neuroprotective agents? (English)

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8 October 2017

Hunter AJ

1

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PubMed ID

9550943

8 October 2017

Mackay KB

series ordinal

2

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PubMed ID

9550943

8 October 2017

Rogers DC

series ordinal

3

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8 October 2017

1 February 1998

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Trends in Pharmacological Sciences

8 October 2017

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8 October 2017

19

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8 October 2017

2

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8 October 2017

59-66

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Cognitive and motor deficits in selected unilateral brain-injured patients

8 October 2017

1 reference

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7 January 2021

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7 January 2021

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7 January 2021

Cognitive deficits in ischemic strokes: psychometric, electrophysiological and cranial tomographic assessment.

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7 January 2021

Cognitive deficits induced by global cerebral ischaemia: relationship to brain damage and reversal by transplants

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7 January 2021

Cognitive deficits induced by global cerebral ischaemia: prospects for transplant therapy

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7 January 2021

Dementia after stroke is a predictor of long-term survival

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7 January 2021

Amnesia with hippocampal lesions after cardiopulmonary arrest.

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7 January 2021

Delayed hippocampal damage in humans following cardiorespiratory arrest.

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7 January 2021

Further characterization of patients with amnesia after cardiac arrest: preserved recognition memory.

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7 January 2021

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

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7 January 2021

Depression and cognitive decline after coronary artery bypass grafting.

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7 January 2021

Magnetic resonance imaging of the hippocampal formation and mammillary nuclei distinguish medial temporal lobe and diencephalic amnesia

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7 January 2021

Animal models of acute ischaemic stroke: can they predict clinically successful neuroprotective drugs?

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7 January 2021

Locomotor hyperactivity and hippocampal CA1 injury after transient forebrain ischemia of gerbils.

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7 January 2021

Locomotor activity in the ischemic gerbil.

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7 January 2021

The use of locomotor activity as a behavioral screen for neuronal damage following transient forebrain ischemia in gerbils.

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7 January 2021

Cerebral ischemia, locomotor activity and spatial mapping.

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7 January 2021

Reference and working memory of rats following hippocampal damage induced by transient forebrain ischemia.

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7 January 2021

Preoperative training modifies radial maze performance in rats with ischemic hippocampal injury.

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7 January 2021

Motor performance in rats exposed to severe forebrain ischemia: effect of fasting and 1,3-butanediol.

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7 January 2021

Long-term neurological assessment of the post-resuscitative effects of flunarizine, verapamil and nimodipine in a new model of global complete ischaemia.

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7 January 2021

Spatial learning is affected by transient occlusion of common carotid arteries (2VO): comparison of behavioural and histopathological changes after '2VO' and 'four-vessel-occlusion' in rats.

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7 January 2021

Ischemia-induced irreversible deficit of memory function in gerbils

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7 January 2021

U-50,488H, a kappa-opioid receptor agonist, markedly prevents memory dysfunctions induced by transient cerebral ischemia in mice

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7 January 2021

Progressive cognitive impairment following chronic cerebral hypoperfusion induced by permanent occlusion of bilateral carotid arteries in rats.

1 reference

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7 January 2021

Behavioral performance of rats following transient forebrain ischemia.

1 reference

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7 January 2021

Effects of fetal hippocampal field grafts on ischaemic-induced deficits in spatial navigation in the water maze.

1 reference

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7 January 2021

Global ischaemia: hippocampal pathology and spatial deficits in the water maze.

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7 January 2021

An animal model of human-type memory loss based on aging, lesion, forebrain ischemia, and drug studies with the rat.

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7 January 2021

Neurobehavioral deficit due to ischemic brain damage limited to half of the CA1 sector of the hippocampus.

1 reference

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7 January 2021

Ischemic tolerance to memory impairment associated with hippocampal neuronal damage after transient cerebral ischemia in rats

1 reference

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7 January 2021

Quantitative effects of cerebral infarction on spatial learning in rats

1 reference

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7 January 2021

Cerebral embolization leads to memory impairment of several learning tasks in rats

1 reference

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7 January 2021

Mnemonic and neuropathological effects of occluding the posterior cerebral artery in Macaca mulatta.

1 reference

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7 January 2021

The neuroprotective actions of chlormethiazole.

1 reference

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7 January 2021

Protection against post-ischemic behavioral pathology by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) in the gerbil

1 reference

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7 January 2021

Relationship between brain damage and memory impairment in rats exposed to transient forebrain ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia.

1 reference

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7 January 2021

Functional, behavioral, and histological changes induced by transient global cerebral ischemia in rats: effects of cinnarizine and flunarizine

1 reference

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7 January 2021

Blockade of 5-HT2 receptors protects against impairment of working memory following transient forebrain ischemia in the rat

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7 January 2021

Embryonic transplantation and ischemic memory deficit.

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7 January 2021

Insulin protects cognitive function in experimental stroke

1 reference

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7 January 2021

New models of focal cerebral ischaemia

1 reference

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7 January 2021

Assessment of functional impairment following permanent middle cerebral artery occlusion in a non-human primate species

1 reference

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7 January 2021

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1 reference

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7 January 2021

Middle cerebral artery occlusion in rats: a neurological and pathological evaluation of a reproducible model

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7 January 2021

Neurologic and neuropathologic outcome after middle cerebral artery occlusion in rats

1 reference

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7 January 2021

Neuroprotective effect of recombinant neutrophil inhibitory factor in transient focal cerebral ischaemia in the rat.

1 reference

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7 January 2021

Behavioral changes after focal cerebral ischemia by left middle cerebral artery occlusion in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Spatial memory disturbance after focal cerebral ischemia in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Genetic hypertension and increased susceptibility to cerebral ischemia

1 reference

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7 January 2021

Long-term spatial cognitive impairment following middle cerebral artery occlusion in rats. A behavioral study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Locomotor and passive avoidance deficits following occlusion of the middle cerebral artery

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Motor dysfunction in a photothrombotic focal ischaemia model.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Behavioral studies on rats with transient cerebral ischemia induced by occlusion of the middle cerebral artery

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

The differential effect of right versus left hemispheric cerebral infarction on catecholamines and behavior in the rat

1 reference

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7 January 2021

Sensorimotor performance and rotation correlate to lesion size in right but not left hemisphere brain infarcts in the spontaneously hypertensive rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Sensorimotor impairments in Wistar Kyoto rats with cerebral infarction, induced by unilateral occlusion of the middle cerebral artery: recovery of function

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Motor performance, histologic damage, and calcium influx in rats treated with NBQX after focal ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Interrelationship of brain edema, motor deficits, and memory impairment in rats exposed to focal ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

An alternative method for the quantitation of neuronal damage after experimental middle cerebral artery occlusion in rats: analysis of behavioral deficit.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Correlation between motor impairment and infarct volume after permanent and transient middle cerebral artery occlusion in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Paw-reaching, sensorimotor, and rotational behavior after brain infarction in rats.

1 reference

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7 January 2021

Behavioural assessment of endothelin-1 induced middle cerebral artery occlusion in the rat.

1 reference

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7 January 2021

Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats.

1 reference

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7 January 2021

Photochemically induced thrombosis of the precentral cortex impairs operant variable-interval spatial delayed alternation performance by rats

1 reference

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7 January 2021

Photothrombotic lesions of the frontal cortex impair the performance of the delayed non-matching to position task by rats

1 reference

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7 January 2021

Photothrombotic lesions of the rat cortex impair acquisition of the water maze.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

GM1 ganglioside reduces cognitive dysfunction after focal cortical ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Neurological and behavioral outcomes of focal cerebral ischemia in rats

1 reference

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7 January 2021

YM796, a novel muscarinic agonist, improves the impairment of learning behavior in a rat model of chronic focal cerebral ischemia.

1 reference

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7 January 2021

Ciliary neurotrophic factor attenuates spatial cognition impairment, cortical infarction and thalamic degeneration in spontaneously hypertensive rats with focal cerebral ischemia.

1 reference

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7 January 2021

Long-Term Spatial Cognitive Impairment after Middle Cerebral Artery Occlusion in Rats: No Involvement of the Hippocampus

1 reference

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7 January 2021

Disturbance of retention of memory after focal cerebral ischemia in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Effects of RGH-2202 on behavioral deficits after focal cerebral ischemia in rats.

1 reference

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7 January 2021

Long-term beneficial effects of BW619C89 on neurological deficit, cognitive deficit and brain damage after middle cerebral artery occlusion in the rat.

1 reference

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7 January 2021

Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance.

1 reference

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7 January 2021

Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Postischemic breakdown in hippocampal protein synthesis and mnesic deficits in rats: Pharmacological improvement by curative naftidrofuryl treatment

1 reference

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7 January 2021

Induction of reproducible brain infarction by photochemically initiated thrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Thrombosis of parietal, but not striate, cortex impairs acquisition of a 14-unit T-maze in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

HU-211, a novel noncompetitive N-methyl-D-aspartate antagonist, improves neurological deficit and reduces infarct volume after reversible focal cerebral ischemia in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Adenosine kinase inhibition protects brain against transient focal ischemia in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Intracisternal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Neurobehavioral consequences of induced spreading depression following photothrombotic middle cerebral artery occlusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

1 reference

7 January 2021

Impaired object recognition memory in rats following ischemia-induced damage to the hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2897%2901157-7

7 January 2021

Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions.

1 reference

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7 January 2021

10.1016/S0165-6147(97)01157-7

Identifiers

DOI

1 reference

8 October 2017

1 reference

PubMed ID

9550943