An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates (Q41757537)

8 October 2017

An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates (English)

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8 October 2017

Xiang H

1

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8 October 2017

Tschirret-Guth RA

series ordinal

2

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8 October 2017

Ortiz De Montellano PR

series ordinal

3

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8 October 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

8 October 2017

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8 October 2017

275

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8 October 2017

46

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8 October 2017

35999-36006

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An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea.

8 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Structure of cytochrome P450eryF involved in erythromycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Purification and reconstitution of the electron transport components for 6-deoxyerythronolide B hydroxylase, a cytochrome P-450 enzyme of macrolide antibiotic (erythromycin) biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Cloning and heterologous expression of the genes encoding nonspecific electron transport components for a cytochrome P450 system of Saccharopolyspora erythraea involved in erythromycin production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Substrate-assisted catalysis in cytochrome P450eryF.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005811200

The catalytic pathway of cytochrome p450cam at atomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Involvement of lysine-88 of spinach ferredoxin-NADP+ reductase in the interaction with ferredoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Expression in Escherichia coli of ferredoxin:NADP+ reductase from spinach. Bacterial synthesis of the holoflavoprotein and of an active enzyme form lacking the first 28 amino acid residues of the sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Bacterial P-450cam methylene monooxygenase components: cytochrome m, putidaredoxin, and putidaredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

The role of Thr268 in oxygen activation of cytochrome P450BM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Role of Glu318 at the putative distal site in the catalytic function of cytochrome P450d

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Chimeric cDNA expression and site directed mutagenesis studies of cytochrome P450s CYP2A1 and CYP2A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Deuterium magic angle spinning studies of substrates bound to cytochrome P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Macrolide antibiotic biosynthesis: isolation and properties of two forms of 6-deoxyerythronolide B hydroxylase from Saccharopolyspora erythraea (Streptomyces erythreus)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Substrate specificity of 6-deoxyerythronolide B hydroxylase, a bacterial cytochrome P450 of erythromycin A biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Rapid procedure for the preparation of ferredoxin-NADP+ oxidoreductase in molecularly pure form at 36 kDa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Thr268 in substrate binding and catalysis in P450BM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

Molecular modeling of cytochrome P450 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005811200

21 January 2018

Identifiers

DOI

10.1074/JBC.M005811200

1 reference

8 October 2017

1 reference