A computational study on thiourea analogs as potent MK-2 inhibitors (Q41763334)

9 October 2017

A computational study on thiourea analogs as potent MK-2 inhibitors (English)

1 reference

9 October 2017

Ming Hao

1

0 references

Jieshan Qiu

object named as

Jieshan Qiu

5

0 references

author name string

Hong Ren

2

1 reference

9 October 2017

Fang Luo

3

1 reference

9 October 2017

Shuwei Zhang

4

1 reference

9 October 2017

Mingjuan Ji

6

1 reference

9 October 2017

Hongzong Si

7

1 reference

9 October 2017

Guohui Li

8

1 reference

9 October 2017

language of work or name

English

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publication date

8 June 2012

1 reference

International Journal of Molecular Sciences

9 October 2017

1 reference

9 October 2017

13

1 reference

9 October 2017

6

1 reference

9 October 2017

7057-7079

1 reference

Creative Commons Attribution 4.0 International

9 October 2017

start time

8 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Structure-based lead identification of ATP-competitive MK2 inhibitors

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Benzothiophene inhibitors of MK2. Part 1: structure-activity relationships, assessments of selectivity and cellular potency

6 June 2018

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Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency

6 June 2018

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Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).

6 June 2018

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Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

6 June 2018

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Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

6 June 2018

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The discovery of carboline analogs as potent MAPKAP-K2 inhibitors

6 June 2018

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Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

6 June 2018

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Structural basis for a high affinity inhibitor bound to protein kinase MK2

6 June 2018

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p38 MAP kinase inhibitors: many are made, but few are chosen.

6 June 2018

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6 June 2018

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Feedback control of the protein kinase TAK1 by SAPK2a/p38

6 June 2018

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Rational selection of training and test sets for the development of validated QSAR models

6 June 2018

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6 June 2018

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6 June 2018

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The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

6 June 2018

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The future role of anti-tumour necrosis factor (TNF) products in the treatment of rheumatoid arthritis

6 June 2018

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Insights into the structural requirements of PKCβII inhibitors based on HQSAR and CoMSIA analyses

6 June 2018

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Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.

18 August 2018

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Exploring QSARs for inhibitory activity of non-peptide HIV-1 protease inhibitors by GA-PLS and GA-SVM.

18 August 2018

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Support vector machines: development of QSAR models for predicting anti-HIV-1 activity of TIBO derivatives

18 August 2018

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Development of predictive 3D-QSAR CoMFA and CoMSIA models for beta-aminohydroxamic acid-derived tumor necrosis factor-alpha converting enzyme inhibitors.

18 August 2018

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Structural analysis of carboline derivatives as inhibitors of MAPKAP K2 using 3D QSAR and docking studies.

18 August 2018

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Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity.

18 August 2018

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Synthesis and SAR studies of indole-based MK2 inhibitors

18 August 2018

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3D-quantitative structure-activity relationship studies on benzothiadiazepine hydroxamates as inhibitors of tumor necrosis factor-alpha converting enzyme

18 August 2018

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Prediction of ozone tropospheric degradation rate constants by projection pursuit regression.

18 August 2018

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Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).

18 August 2018

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Use of MM-PBSA in reproducing the binding free energies to HIV-1 RT of TIBO derivatives and predicting the binding mode to HIV-1 RT of efavirenz by docking and MM-PBSA.

18 August 2018

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Comparison of simple potential functions for simulating liquid water

18 August 2018

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https://api.crossref.org/works/10.3390%2FIJMS13067057

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

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A Novel QSAR Model for Evaluating and Predicting the Inhibition Activity of Dipeptidyl Aspartyl Fluoromethylketones

21 January 2018

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MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis

21 January 2018

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12 December 2020

QSAR study of flavonoids and biflavonoids as influenza H1N1 virus neuraminidase inhibitors

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12 December 2020

Pyrazinoindolone inhibitors of MAPKAP-K2

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12 December 2020

Molecular dynamics simulations of hexahydro-1,3,5-trinitro-1,3,5-s-triazine (RDX) using a combined Sorescu-Rice-Thompson AMBER force field

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12 December 2020

Novel tetrahydro-beta-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

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12 December 2020

Identifiers

DOI

10.3390/IJMS13067057

1 reference

9 October 2017

1 reference

9 October 2017

PubMed publication ID

22837679

1 reference