Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia. (Q41771344)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729465%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729465%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

0 references

7

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11 February 2020

Sophie Erhardt

8

1 reference

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11 February 2020

author name string

Klas R Linderholm

1

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11 February 2020

Elisabeth Skogh

2

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11 February 2020

Sara K Olsson

3

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11 February 2020

Marja-Liisa Dahl

4

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11 February 2020

Maria Holtze

5

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11 February 2020

Göran Engberg

6

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11 February 2020

language of work or name

English

0 references

publication date

20 August 2010

1 reference

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11 February 2020

published in

Schizophrenia Bulletin

1 reference

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11 February 2020

volume

38

1 reference

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11 February 2020

issue

3

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11 February 2020

page(s)

426-432

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Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder

11 February 2020

cites work

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Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior

6 June 2018

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6 June 2018

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The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex

6 June 2018

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Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice

6 June 2018

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Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release

6 June 2018

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Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum.

6 June 2018

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From inflammation to sickness and depression: when the immune system subjugates the brain

6 June 2018

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Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions

6 June 2018

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Molecules in focus: indoleamine 2,3-dioxygenase.

6 June 2018

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Elevations of endogenous kynurenic acid produce spatial working memory deficits

6 June 2018

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Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum

6 June 2018

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Increased cortical kynurenate content in schizophrenia

6 June 2018

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The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

6 June 2018

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Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

6 June 2018

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Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons

6 June 2018

1 reference

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Tripartite synapses: glia, the unacknowledged partner

6 June 2018

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(R,S)-3,4-dichlorobenzoylalanine (FCE 28833A) causes a large and persistent increase in brain kynurenic acid levels in rats

6 June 2018

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Identification and quantification of kynurenic acid in human brain tissue.

6 June 2018

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Presence of Kynurenic Acid in the Mammalian Brain

6 June 2018

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Cerebrospinal fluid levels of quinolinic acid in Huntington's disease and schizophrenia

6 June 2018

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Prestimulus effects on human startle reflex in normals and schizophrenics

6 June 2018

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Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase.

6 June 2018

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L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning.

18 August 2018

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Elevated levels of kynurenic acid change the dopaminergic response to amphetamine: implications for schizophrenia

18 August 2018

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Induction of the kynurenine pathway by neurotropic influenza A virus infection

18 August 2018

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Clozapine interacts with the glycine site of the NMDA receptor: electrophysiological studies of dopamine neurons in the rat ventral tegmental area

18 August 2018

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Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder

18 August 2018

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Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis

18 August 2018

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Temporal context discrimination in patients with schizophrenia: associations with auditory hallucinations and negative symptoms.

18 August 2018

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Increased concentration of cerebral kynurenic acid alters stimulus processing and conditioned responding

18 August 2018

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Chronic neuroleptic treatment reduces endogenous kynurenic acid levels in rat brain

18 August 2018

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Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder

18 August 2018

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Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid

18 August 2018

1 reference

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Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329991

Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease

18 August 2018

1 reference

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Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329991

Endogenous kynurenic acid disrupts prepulse inhibition

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329991

Context memory and binding in schizophrenia.

18 August 2018

1 reference

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Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

18 August 2018

1 reference

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Inhibitory action of clozapine on rat ventral tegmental area dopamine neurons following increased levels of endogenous kynurenic acid

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329991

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat

18 August 2018

1 reference

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Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329991

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329991

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

18 August 2018

1 reference

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Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20729465

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nicotine-induced excitation of locus coeruleus neurons is blocked by elevated levels of endogenous kynurenic acid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20729465

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Excitation of nigral dopamine neurons by the GABA(A) receptor agonist muscimol is mediated via release of glutamate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20729465

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/SCHBUL/SBQ086

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729465%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729465%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

20729465

1 reference