Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes. (Q41790884)

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29 February 2020

title

Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes (English)

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2

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author name string

Katsutoshi Miyagawa

1

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29 February 2020

Rieko Goto

3

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29 February 2020

Rina Matsuyama

4

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29 February 2020

Kaoru Ono

5

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29 February 2020

Sayaka Kitano

6

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29 February 2020

Shuji Kawasaki

7

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29 February 2020

Motoyuki Igata

8

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29 February 2020

Junji Kawashima

9

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29 February 2020

Takeshi Matsumura

10

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29 February 2020

Hiroyuki Motoshima

11

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29 February 2020

Eiichi Araki

12

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language of work or name

English

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publication date

4 November 2013

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Cardiovascular Diabetology

29 February 2020

published in

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volume

12

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29 February 2020

page(s)

160

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https://scigraph.springernature.com/pub.10.1186/1475-2840-12-160

29 February 2020

exact match

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cites work

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Mechanisms of protective effects induced by blockade of the renin-angiotensin system: novel role of the pancreatic islet angiotensin-generating system in Type 2 diabetes.

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The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

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Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes.

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18 August 2018

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Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]m

18 August 2018

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Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice.

18 August 2018

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18 August 2018

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Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes

18 August 2018

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Acute and chronic effects of the incretin enhancer vildagliptin in insulin-resistant rats

18 August 2018

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Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity

18 August 2018

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Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action

18 August 2018

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Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.

18 August 2018

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Pharmacodynamics of Vildagliptin in Patients With Type 2 Diabetes During OGTT

18 August 2018

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Crossref

https://api.crossref.org/works/10.1186%2F1475-2840-12-160

The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats

21 January 2018

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12 December 2020

Valsartan protects against ER stress-induced myocardial apoptosis via CHOP/Puma signaling pathway in streptozotocin-induced diabetic rats

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12 December 2020

Impact of the dipeptidyl peptidase-4 inhibitor vildagliptin on glucose tolerance and β-cell function and mass in insulin receptor substrate-2-knockout mice fed a high-fat diet

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12 December 2020

DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice

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12 December 2020

Enhanced beta cell function and anti-inflammatory effect after chronic treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin in an advanced-aged diet-induced obesity mouse model

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12 December 2020

Reduced incretin effect in type 2 (non-insulin-dependent) diabetes

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12 December 2020

Identifiers

DOI

10.1186/1475-2840-12-160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24188631%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

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29 February 2020

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