P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice (Q41813517)

12 October 2017

P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice (English)

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12 October 2017

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5

Wolfram Ruf

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12 October 2017

Christian Furlan-Freguia

1

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12 October 2017

Patrizia Marchese

2

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12 October 2017

András Gruber

3

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12 October 2017

Zaverio M Ruggeri

4

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12 October 2017

language of work or name

English

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publication date

13 June 2011

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Journal of Clinical Investigation

12 October 2017

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12 October 2017

121

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12 October 2017

7

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12 October 2017

2932-2944

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describes a project that uses

12 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3127437/fullTextXML

inferred from PubMed Central ID database lookup

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Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

6 June 2018

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Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity

6 June 2018

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A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

6 June 2018

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Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure.

6 June 2018

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Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption

6 June 2018

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P2X(7) Receptors in Neurological and Cardiovascular Disorders

6 June 2018

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Carbohydrates and activity of natural and recombinant tissue factor

6 June 2018

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6 June 2018

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P2X7 receptor activates multiple selective dye-permeation pathways in RAW 264.7 and human embryonic kidney 293 cells

6 June 2018

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Acid sphingomyelinase activity triggers microparticle release from glial cells

6 June 2018

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Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury

6 June 2018

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Mechanisms of thrombus formation

6 June 2018

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A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes.

6 June 2018

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Interaction and functional association of protein disulfide isomerase with alphaVbeta3 integrin on endothelial cells

6 June 2018

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A critical role for extracellular protein disulfide isomerase during thrombus formation in mice

6 June 2018

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Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation

6 June 2018

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Tissue factor activation: is disulfide bond switching a regulatory mechanism?

6 June 2018

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Liaisons dangereuses: P2X(7) and the inflammasome.

6 June 2018

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Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages

6 June 2018

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Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia.

6 June 2018

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Murine macrophage P2X7 receptors support rapid prothrombotic responses

6 June 2018

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Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway

6 June 2018

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Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

6 June 2018

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Disulfide isomerization switches tissue factor from coagulation to cell signaling

6 June 2018

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6 June 2018

Tissue factor encryption

1 reference

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Factor V Leiden improves in vivo hemostasis in murine hemophilia models

6 June 2018

1 reference

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Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells

6 June 2018

1 reference

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Defective thrombus formation in mice lacking coagulation factor XII

6 June 2018

1 reference

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Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78.

6 June 2018

1 reference

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Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation.

6 June 2018

1 reference

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Acute cholesterol depletion impairs functional expression of tissue factor in fibroblasts: modulation of tissue factor activity by membrane cholesterol

6 June 2018

1 reference

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Platelet cell-surface protein disulphide-isomerase mediated S-nitrosoglutathione consumption

6 June 2018

1 reference

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Lipid rafts are necessary for tonic inhibition of cellular tissue factor procoagulant activity

6 June 2018

1 reference

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Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.

6 June 2018

1 reference

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Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X(7).

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Proteomic and functional evidence for a P2X7 receptor signalling complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Mechanism of transfer of NO from extracellular S-nitrosothiols into the cytosol by cell-surface protein disulfide isomerase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Altered cytokine production in mice lacking P2X(7) receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

CD40 ligation induces tissue factor expression in human vascular smooth muscle cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Cytolytic P2X purinoceptors.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Lysine residues 165 and 166 are essential for the cofactor function of tissue factor.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Critical importance of the cell system when studying tissue factor de-encryption

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Role for nitric oxide in permeability of hippocampal neuronal hemichannels during oxygen glucose deprivation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Characterization of the S-denitrosation activity of protein disulfide isomerase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

P2X7 receptor activation-induced contraction and lysis in human saphenous vein smooth muscle.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127437

Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release

18 August 2018

1 reference

12 December 2020

An anti-tissue factor monoclonal antibody which inhibits TF.VIIa complex is a potent anticoagulant in plasma

1 reference

12 December 2020

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

1 reference

12 December 2020

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

1 reference

12 December 2020

Evidence for activation of tissue factor by an allosteric disulfide bond

1 reference

12 December 2020

Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles

1 reference

12 December 2020

Mechanism of tissue factor activation on HL-60 cells

1 reference

12 December 2020

Studies of the mechanism for enhanced cell surface factor VIIa/tissue factor activation of factor X on fibroblast monolayers after their exposure to N-ethylmaleimide

1 reference

12 December 2020

Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation

1 reference

12 December 2020

Reanalysis of P2X7 receptor expression in rodent brain

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI46129

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

21670495

1 reference