Methylome alterations "mark" new therapeutic opportunities in glioblastoma. (Q41817337)

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15 February 2020

title

Methylome alterations "mark" new therapeutic opportunities in glioblastoma (English)

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15 February 2020

1

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2

Charles G Eberhart

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15 February 2020

publication date

1 October 2012

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15 February 2020

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volume

22

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15 February 2020

issue

4

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15 February 2020

page(s)

417-418

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

15 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

An integrated genomic analysis of human glioblastoma multiforme

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

The 2007 WHO classification of tumours of the central nervous system

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4612575

10.1016/J.CCR.2012.10.001

18 August 2018

Identifiers

DOI

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15 February 2020

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15 February 2020

PubMed publication ID

23079650

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