T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs (Q41826109)

12 October 2017

T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs (English)

1 reference

12 October 2017

Stotz SH

1

1 reference

12 October 2017

Bolliger L

series ordinal

2

1 reference

12 October 2017

Carbone FR

series ordinal

3

1 reference

12 October 2017

Palmer E

series ordinal

4

1 reference

12 October 2017

language of work or name

English

0 references

publication date

1 January 1999

1 reference

Journal of Experimental Medicine

12 October 2017

1 reference

12 October 2017

189

1 reference

12 October 2017

2

1 reference

12 October 2017

253-264

1 reference

Three-dimensional segregation of supramolecular activation clusters in T cells

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Formation of TCR dimers/trimers as a crucial step for T cell activation.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Persistence of peptide-induced CD4+ T cell anergy in vitro

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

TCR alpha-chain usage can determine antigen-selected TCR beta-chain repertoire diversity.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Variant TCR ligands: new insights into the molecular basis of antigen-dependent signal transduction and T-cell activation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Selective activation of the calcium signaling pathway by altered peptide ligands

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Complex complexes: signaling at the TCR.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

T cell antigen receptor signal transduction pathways

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Partial signaling by CD8+ T cells in response to antagonist ligands

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Kinetic discrimination in T-cell activation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

T-cell-receptor affinity and thymocyte positive selection

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Essential flexibility in the T-cell recognition of antigen

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Regulation of lymphocyte function by protein phosphorylation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

T cell receptor antagonist peptides induce positive selection

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Antigen analogs/MHC complexes as specific T cell receptor antagonists

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Specificity and flexibility in thymic selection

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Ligands for the T-cell receptor: hard times for avidity models

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Kinetic proofreading in T-cell receptor signal transduction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

T cell receptor antagonists and partial agonists

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Flow cytometry as an analytical and preparative tool in immunology

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Identification of a monoclonal antibody specific for a murine T3 polypeptide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Contingent genetic regulatory events in T lymphocyte activation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Improved retroviral vectors for gene transfer and expression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

The interleukin-2 T-cell system: a new cell growth model.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

The duration of antigenic stimulation determines the fate of naive and effector T cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Developmental regulation of the TCR zeta-chain. Differential expression and tyrosine phosphorylation of the TCR zeta-chain in resting immature and mature T lymphocytes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192976

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant

18 August 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α-mRNA of BW5147 origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Monoclonal antibodies raised against engineered soluble mouse T cell receptors and specific for Vα8-, Vβ2- or Vβ10-bearing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Cooperative interaction of B lymphocytes with antigen-specific helper T lymphocytes is MHC restricted

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Gene transfer experiments imply instructive role of major histocompatibility complex class I molecules in cellular peptide processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

The short extracellular domain of the T cell receptor zeta chain is involved in assembly and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.2.253

Class I and class II MHC gene products differentially affect the fate of V beta 5 bearing thymocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9892608

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9892608

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pre-TCR/CD3 and TCR/CD3 complexes: decamers with differential signalling properties?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9892608

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.189.2.253

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

9892608

1 reference