Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats. (Q41835936)

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scientific article published on July 2000

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English	Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.	scientific article published on July 2000

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8 November 2019

Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats (English)

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8 November 2019

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ChEBI release 2020-05-28

Colin T Dourish

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8 November 2019

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S P Vickers

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8 November 2019

K R Benwell

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8 November 2019

R H Porter

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8 November 2019

M J Bickerdike

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8 November 2019

G A Kennett

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1 July 2000

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8 November 2019

British Journal of Pharmacology

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8 November 2019

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8 November 2019

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8 November 2019

1305-1314

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8 November 2019

Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

1 reference

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5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential

1 reference

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6 June 2018

Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice.

1 reference

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6 June 2018

Effect of chronic m-CPP on locomotion, hypophagia, plasma corticosterone and 5-HT2C receptor levels in the rat

1 reference

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6 June 2018

5-HT2C receptor activation decreases appetite and body weight in obese subjects

1 reference

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6 June 2018

Direct injection of 5-HT2A receptor agonists into the medial prefrontal cortex produces a head-twitch response in rats.

1 reference

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6 June 2018

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

1 reference

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6 June 2018

BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats

1 reference

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6 June 2018

Identification of an endogenous 5-hydroxytryptamine2A receptor in NIH-3T3 cells: agonist-induced down-regulation involves decreases in receptor RNA and number.

1 reference

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6 June 2018

Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing

1 reference

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6 June 2018

The human serotonin 5-HT2C receptor: complete cDNA, genomic structure, and alternatively spliced variant

1 reference

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6 June 2018

The lateral hypothalamic area revisited: ingestive behavior

1 reference

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6 June 2018

Multiple serotonin receptors: opportunities for new treatments for obesity?

1 reference

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6 June 2018

Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature

1 reference

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6 June 2018

Suppression of behavioral activity by norfenfluramine and related drugs in rats is not mediated by serotonin release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Effects of housing, restraint and chronic treatments with mCPP and sertraline on behavioural responses to mCPP.

1 reference

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6 June 2018

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

1 reference

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6 June 2018

Neurobiology of an anorectic drug: fenfluramine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Evidence that mCPP may have behavioural effects mediated by central 5-HT1C receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Infusion of the 5-hydroxytryptamine agonists RU24969 and TFMPP into the paraventricular nucleus of the hypothalamus causes hypophagia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Effect of continuous infusions of dexfenfluramine on food intake, body weight and brain amines in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Tolerance to fenfluramine anorexia: fact or fiction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Sibutramine in weight control: a dose-ranging, efficacy study

1 reference

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6 June 2018

Comparative studies on the anorectic activity of d-fenfluramine in mice, rats, and guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Clinical studies with d-fenfluramine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Effects of chronically administered fluoxetine and fenfluramine on food intake, body weight and the behavioural satiety sequence

1 reference

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6 June 2018

Chronic treatment with meta-chlorophenylpiperazine (m-CPP) alters behavioral and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2(di-N-propylamino)tetralin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Fluoxetine attenuates the DL-fenfluramine-induced increase in extracellular serotonin as measured by in vivo dialysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

6 June 2018

Semiquantitative analysis of low levels of mRNA expression from small amounts of brain tissue by nonradioactive reverse transcriptase-polymerase chain reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

18 August 2018

Quantitation of nicotinic acetylcholine receptor subunits alpha 4 and beta 2 messenger RNA in postmortem human brain using a non-radioactive RT-PCR and CCD imaging system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

18 August 2018

Ritanserin attenuates anorectic, endocrine and thermic responses to d-fenfluramine in human volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572202

18 August 2018

(—)-m-Chlorophenyl-piperazine, a central 5-hydroxytryptamine agonist, is a metabolite of trazodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that d-fenfluramine anorexia is mediated by 5-HT1 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel regulation of 5-HT1C receptors: down-regulation induced both by 5-HT1C/2 receptor agonists and antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermogenesis, brown adipose tissue and dexfenfluramine in animal studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute effect of dexfenfluramine on resting metabolic rate and postprandial thermogenesis in obese subjects: a double-blind placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single and multiple dose pharmacokinetics of nefazodone in subjects classified as extensive and poor metabolizers of dextromethorphan

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology of 5-HT receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic fenfluramine treatment: effects on body weight, food intake and energy expenditure

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-chlorophenylpiperazine induced changes in locomotor activity are mediated by 5-HT1 as well as 5-HT2C receptors in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of selective tolerance to the serotonin behavioral syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPP

1 reference

https://pubmed.ncbi.nlm.nih.gov/10903970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0703443

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8 November 2019

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Europe PubMed Central

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8 November 2019

1 reference

Europe PubMed Central

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8 November 2019

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