Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets (Q41841024)

13 October 2017

Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets (English)

1 reference

13 October 2017

Analia Garcia

1

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13 October 2017

Haripriya Shankar

2

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13 October 2017

Swaminathan Murugappan

3

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13 October 2017

Soochong Kim

4

1 reference

13 October 2017

Satya P Kunapuli

5

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13 October 2017

language of work or name

English

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publication date

1 June 2007

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13 October 2017

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13 October 2017

404

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13 October 2017

2

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13 October 2017

299-308

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Nucleotide receptor signaling in platelets

13 October 2017

1 reference

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P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation

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1 reference

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Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3

6 June 2018

1 reference

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Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets

6 June 2018

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Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets

6 June 2018

1 reference

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Effect of selective inhibition of the p38 MAP kinase pathway on platelet aggregation

6 June 2018

1 reference

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Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways

6 June 2018

1 reference

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Role of the Pyk2-MAP kinase-cPLA2 signaling pathway in shear-dependent platelet aggregation

6 June 2018

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A novel Galphaq/11-selective inhibitor

6 June 2018

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ADP secretion and subsequent P2Y12 receptor signalling play a crucial role in thrombin-induced ERK2 activation in human platelets

6 June 2018

1 reference

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P2X1-mediated ERK2 Activation Amplifies the Collagen-induced Platelet Secretion by Enhancing Myosin Light Chain Kinase Activation

6 June 2018

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Platelet purinergic receptors

6 June 2018

1 reference

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P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen

6 June 2018

1 reference

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Protein kinase C alpha -mediated negative feedback regulation is responsible for the termination of insulin-like growth factor I-induced activation of nuclear phospholipase C beta1 in Swiss 3T3 cells

6 June 2018

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Novel platelet inhibitors

6 June 2018

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ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets

6 June 2018

1 reference

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Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs

6 June 2018

1 reference

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The role of heterotrimeric G proteins in platelet activation

6 June 2018

1 reference

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The P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human platelets

6 June 2018

1 reference

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Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways

6 June 2018

1 reference

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ADP receptors and clinical bleeding disorders

6 June 2018

1 reference

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Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape change

6 June 2018

1 reference

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Comparative antiplatelet effects of aspirin, vapiprost and GR144053, a GPIIb/IIIa antagonist, with a special reference to the role of platelet microaggregates

6 June 2018

1 reference

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Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

6 June 2018

1 reference

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Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

6 June 2018

1 reference

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Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets

6 June 2018

1 reference

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cPLA2 is phosphorylated and activated by MAP kinase

6 June 2018

1 reference

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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

6 June 2018

1 reference

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Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid

6 June 2018

1 reference

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Relative contribution of G-protein-coupled pathways to protease-activated receptor-mediated Akt phosphorylation in platelets

6 June 2018

1 reference

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Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner

18 August 2018

1 reference

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Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets.

18 August 2018

1 reference

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Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.

18 August 2018

1 reference

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Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets

18 August 2018

1 reference

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Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets

18 August 2018

1 reference

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Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin

18 August 2018

1 reference

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Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors

18 August 2018

1 reference

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Genetic and pharmacological analyses of involvement of Src-family, Syk and Btk tyrosine kinases in platelet shape change. Src-kinases mediate integrin alphaIIb beta3 inside-out signalling during shape change.

18 August 2018

1 reference

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Evidence for a role for phospholipase C, but not phospholipase A2, in platelet activation in response to low concentrations of collagen

18 August 2018

1 reference

12 December 2020

Regulation of RAS in human platelets

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12 December 2020

A role for p38 MAP kinase in platelet activation by von Willebrand factor

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12 December 2020

Synergistic release of arachidonic acid from platelets by activators of protein kinase C and Ca2+ ionophores. Evidence for the role of protein phosphorylation in the activation of phospholipase A2 and independence from the Na+/H+ exchanger

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12 December 2020

Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents

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12 December 2020

Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase

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12 December 2020

Thrombin induces activation of p38 MAP kinase in human platelets

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12 December 2020

Signaling through G proteins in platelets: to the integrins and beyond

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12 December 2020

Identification of the Src family kinases, Lck and Fgr in platelets. Their tyrosine phosphorylation status and subcellular distribution compared with other Src family members

1 reference

12 December 2020

Direct Inhibition of Cyclooxygenase-1 and -2 by the Kinase Inhibitors SB 203580 and PD 98059

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12 December 2020

A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase

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12 December 2020

Identifiers

DOI

10.1042/BJ20061584

1 reference

13 October 2017

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13 October 2017

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