The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner. (Q41848433)

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scientific article published on 22 November 2013

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English	The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.	scientific article published on 22 November 2013

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The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner (English)

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Harish C Thakur

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Madhurendra Singh

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Daniel Prumbaum

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Eyad Kalawy Fansa

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Hakima Ezzahoini

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Roland P Piekorz

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Jana Kremer

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André Abts

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Lutz Schmitt

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Mohammad R Ahmadian

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1 March 2020

A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells

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Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding

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Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

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A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

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The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program

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XMAP215 regulates microtubule dynamics through two distinct domains.

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Never tear us apart--the importance of centrosome clustering.

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The centrosome and mitotic spindle apparatus in cancer and senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

TACC3-TSC2 maintains nuclear envelope structure and controls cell division.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.532333

21 January 2018

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.532333

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24273164%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24273164%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24273164%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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