High calcium concentration in bones promotes bone metastasis in renal cell carcinomas expressing calcium-sensing receptor (Q41857468)

13 October 2017

High calcium concentration in bones promotes bone metastasis in renal cell carcinomas expressing calcium-sensing receptor (English)

1 reference

13 October 2017

Elke Joeckel

1

1 reference

13 October 2017

Tobias Haber

2

1 reference

13 October 2017

Dirk Prawitt

3

1 reference

13 October 2017

Kerstin Junker

4

1 reference

13 October 2017

Christian Hampel

5

1 reference

13 October 2017

Joachim W Thüroff

6

1 reference

13 October 2017

Frederik C Roos

7

1 reference

13 October 2017

Walburgis Brenner

8

1 reference

13 October 2017

28 February 2014

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13 October 2017

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13 October 2017

13

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13 October 2017

42

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https://scigraph.springernature.com/pub.10.1186/1476-4598-13-42

13 October 2017

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Positive and negative allosteric modulators promote biased signaling at the calcium-sensing receptor.

5 June 2018

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The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH

5 June 2018

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Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway

5 June 2018

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Review article: loss of the calcium-sensing receptor in colonic epithelium is a key event in the pathogenesis of colon cancer.

5 June 2018

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New concepts in calcium-sensing receptor pharmacology and signalling

5 June 2018

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Adhesion of renal carcinoma cells to endothelial cells depends on PKCmu

5 June 2018

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Physiology and pathophysiology of the calcium-sensing receptor in the kidney

5 June 2018

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Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor.

5 June 2018

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Metastasis: from dissemination to organ-specific colonization

5 June 2018

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Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor

5 June 2018

1 reference

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The role of the calcium-sensing receptor in the development and progression of cancer

5 June 2018

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Molecular basis of metastasis.

5 June 2018

1 reference

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Calcium-sensing receptor in cancer: good cop or bad cop?

5 June 2018

1 reference

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The calcium sensing receptor: from understanding parathyroid calcium homeostasis to bone metastases

5 June 2018

1 reference

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Migration of renal carcinoma cells is dependent on protein kinase Cdelta via beta1 integrin and focal adhesion kinase

5 June 2018

1 reference

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The regulation of cell motility and chemotaxis by phospholipid signaling

5 June 2018

1 reference

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The calcium-sensing receptor and its interacting proteins

5 June 2018

1 reference

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Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis

5 June 2018

1 reference

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Roles for the calcium sensing receptor in primary and metastatic cancer.

5 June 2018

1 reference

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Cellular basis of cancer metastasis: A review of fundamentals and new advances

5 June 2018

1 reference

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Expression of the calcium receptor in human breast cancer--a potential new marker predicting the risk of bone metastases

5 June 2018

1 reference

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Mechanisms of bone metastasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Calcium-sensing receptor induces proliferation through p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase but not extracellularly regulated kinase in a model of humoral hypercalcemia of malignancy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

JNK phosphorylates paxillin and regulates cell migration

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

The skeletal metastatic complications of renal cell carcinoma.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Extracellular calcium sensing and extracellular calcium signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Extracellular calcium-sensing receptor induces cellular proliferation and activation of a nonselective cation channel in U373 human astrocytoma cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

General mechanisms of metastasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

The distribution of secondary growths in cancer of the breast. 1889

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Skeletal complications and survival in renal cancer patients with bone metastases.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Treatment of osseous metastases in patients with renal cell carcinoma.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Number of metastatic sites rather than location dictates overall survival of patients with node-negative metastatic renal cell carcinoma

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Signal transduction mechanisms linking increased extracellular calcium to proliferation in ovarian surface epithelial cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Identification and localization of the extracellular calcium-sensing receptor in human breast.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Calcium receptor messenger ribonucleic acid levels in the parathyroid glands and kidney of vitamin D-deficient rats are not regulated by plasma calcium or 1,25-dihydroxyvitamin D3.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945739

Mechanisms of bone metastasis

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24576174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Migration of renal tumor cells depends on dephosphorylation of Shc by PTEN

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24576174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1476-4598-13-42

1 reference

Dimensions Publication ID

13 October 2017

0 references

1 reference

13 October 2017

1 reference