An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteins (Q41869522)

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scientific article published on February 2005

Language	Label	Description	Also known as
English	An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteins	scientific article published on February 2005

Statements

scholarly article

1 reference

Europe PubMed Central

13 October 2017

An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteins (English)

1 reference

Europe PubMed Central

13 October 2017

author name string

Rajendra Mistry

1

1 reference

Europe PubMed Central

13 October 2017

Mark R Dowling

2

1 reference

Europe PubMed Central

13 October 2017

R A John Challiss

3

1 reference

Europe PubMed Central

13 October 2017

language of work or name

0 references

publication date

1 February 2005

1 reference

Europe PubMed Central

13 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

13 October 2017

144

1 reference

Europe PubMed Central

13 October 2017

4

1 reference

Europe PubMed Central

13 October 2017

566-575

1 reference

Europe PubMed Central

13 October 2017

Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications

1 reference

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Ligand-selective receptor conformations revisited: the promise and the problem

1 reference

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5 June 2018

Evidence for cross‐talk between M2 and M3 muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal‐regulated kinase signalling pathways in Chinese hamster ovary cells

1 reference

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Pharmacological discrimination between muscarinic receptor signal transduction cascades with bethanechol chloride

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Agonist-induced conformational changes in the beta2 adrenergic receptor

1 reference

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Agonist trafficking of G(i/o)-mediated alpha(2A)-adrenoceptor responses in HEL 92.1.7 cells

1 reference

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Dual effects of muscarinic M(2) acetylcholine receptors on the synthesis of cyclic AMP in CHO cells: dependence on time, receptor density and receptor agonists

1 reference

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G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

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Opposing effects of protein kinase C and protein kinase A on metabotropic glutamate receptor signaling: selective desensitization of the inositol trisphosphate/Ca2+ pathway by phosphorylation of the receptor-G protein-coupling domain

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Agonist selective regulation of G proteins by cannabinoid CB(1) and CB(2) receptors

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Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

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Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

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Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.

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International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors.

1 reference

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Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

1 reference

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Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.

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Differential signal transduction by five splice variants of the PACAP receptor

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Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies

1 reference

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Differential regulation of cAMP-mediated gene transcription by m1 and m4 muscarinic acetylcholine receptors. Preferential coupling of m4 receptors to Gi alpha-2.

1 reference

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Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

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Human muscarinic receptors expressed in A9L and CHO cells: activation by full and partial agonists

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Differential coupling of m2 and m4 muscarinic receptors to inhibition of adenylyl cyclase by Gi alpha and G(o)alpha subunits

1 reference

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Muscarinic receptors--characterization, coupling and function

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A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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The relationship between muscarinic receptor occupancy and adenylate cyclase inhibition in the rabbit myocardium

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Muscarinic acetylcholine receptor: thermodynamic analysis of the interaction of agonists and antagonists

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Functional responses of cloned muscarinic receptors expressed in CHO-K1 cells

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Characterization of M2 muscarinic receptor activation of different G protein subtypes

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Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.

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Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

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Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells

1 reference

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Modulation of agonist binding by guanine nucleotides in CHO cells expressing muscarinic m1-m5 receptors

1 reference

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Identification of a Gs coupling domain in the amino terminus of the third intracellular loop of the alpha 2A-adrenergic receptor. Evidence for distinct structural determinants that confer Gs versus Gi coupling

1 reference

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M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro

1 reference

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Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s)

1 reference

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Relationship between agonist-induced muscarinic receptor loss and desensitization of stimulated phosphoinositide turnover in two neuroblastomas: methodological considerations

1 reference

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Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655507

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Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors m1-m4

1 reference

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Identifiers

10.1038/SJ.BJP.0706090

1 reference

Europe PubMed Central

13 October 2017

release_cbioru2yyneorhcw4zj3akiiai

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https://api.fatcat.wiki/v0/release/cbioru2yyneorhcw4zj3akiiai

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

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