Expression, purification and characterization of a mouse-human chimeric antibody and chimeric Fab' fragment (Q41870446)

13 October 2017

Expression, purification and characterization of a mouse-human chimeric antibody and chimeric Fab' fragment (English)

1 reference

12 November 2022

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12 November 2022

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12 November 2022

author name string

D. J. King

1

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12 November 2022

J. R. Adair

2

1 reference

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12 November 2022

S. Angal

3

1 reference

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12 November 2022

D. C. Low

4

1 reference

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12 November 2022

K. A. Proudfoot

5

1 reference

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12 November 2022

J. C. Lloyd

6

1 reference

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12 November 2022

M. W. Bodmer

7

1 reference

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12 November 2022

G. T. Yarranton

8

1 reference

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12 November 2022

language of work or name

English

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publication date

1 January 1992

1 reference

PMCID

1130685

13 October 2017

15 January 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1736881

full work available at URL

12 November 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1736881/?tool=EBI

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1736881/pdf/?tool=EBI

12 November 2022

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Portable Document Format

online access status

open access

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https://europepmc.org/articles/PMC1130685

12 November 2022

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https://europepmc.org/articles/PMC1130685?pdf=render

12 November 2022

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https://portlandpress.com/biochemj/article-pdf/281/2/317/606011/bj2810317.pdf

12 November 2022

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Portable Document Format

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12 November 2022

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13 October 2017

281 ( Pt 2)

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13 October 2017

317-323

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Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Radioimmunoscintigraphy in tumour identification

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Escherichia coli secretion of an active chimeric antibody fragment.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Assembly of a functional immunoglobulin Fv fragment in Escherichia coli

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Purification and composition of the human tumor-associated glycoprotein (TAG-72) defined by monoclonal antibodies CC49 and B72.3.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Cloning and high level expression of a chimeric antibody with specificity for human carcinoembryonic antigen.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

A genetically engineered murine/human chimeric antibody retains specificity for human tumor-associated antigen.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17-1A.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Human lymphocyte hybridomas and monoclonal antibodies.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

The construction of a highly efficient and versatile set of mammalian expression vectors.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Mouse/human chimeric monoclonal antibody in man: kinetics and immune response

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Influence of the hinge region on complement activation, C1q binding, and segmental flexibility in chimeric human immunoglobulins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Antibodies from Escherichia coli.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Site-specific attachment to recombinant antibodies via introduced surface cysteine residues

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Human myeloma IgG [immunoglobulin] half-molecules. Structural and antigenic analyses

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Analysis of a human tumor-associated glycoprotein (TAG-72) identified by monoclonal antibody B72.3.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130685

Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3.

18 August 2018

1 reference

12 December 2020

Expression in COS cells of a mouse-human chimaeric B72.3 antibody

1 reference

12 December 2020

Improved radioimaging and tumor localization with monoclonal F(ab')2

1 reference

12 December 2020

Differential reactivity of monoclonal antibodies with human colon adenocarcinomas and adenomas

1 reference

12 December 2020

An in vitro system for studying the kinetics of interchain disulfide bond formation in immunoglobulin G

1 reference

12 December 2020

Anti-murine antibody response to mouse monoclonal antibodies: clinical findings and implications

1 reference

12 December 2020

Recombinant human-mouse chimeric monoclonal antibody specific for common acute lymphocytic leukemia antigen

1 reference

12 December 2020

Comparison of methods for the generation of immunoreactive fragments of a monoclonal antibody (B72.3) reactive with human carcinomas

1 reference

12 December 2020

Improved procedure for preparation of F(ab')2 fragments of mouse IgGs by papain digestion

1 reference

12 December 2020

Characterization and biodistribution of recombinant and recombinant/chimeric constructs of monoclonal antibody B72.3.

1 reference

12 December 2020

Electrophoretic properties of human IgG and its subclasses on sodium dodecyl-sulfate-polyacrylamide gel electrophoresis and immunoblots

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2810317

1 reference

13 October 2017

1 reference

13 October 2017

1 reference

PMCID

1130685