Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy. (Q41872301)

From Wikidata

Jump to navigation Jump to search

scientific article published on January 2003

Language	Label	Description	Also known as
English	Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy.	scientific article published on January 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

dihydrobetulinic acid

1 reference

ChEBI release 2020-05-28

Leishmania donovani

object named as

Leishmania donovani

1 reference

based on heuristic

inferred from title

author name string

Arnab Roy Chowdhury

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Suparna Mandal

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Anindya Goswami

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Monidipa Ghosh

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Labanya Mandal

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Debabani Chakraborty

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Agneyo Ganguly

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Gayatri Tripathi

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Sibabrata Mukhopadhyay

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Santu Bandyopadhyay

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Hemanta K Majumder

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

language of work or name

0 references

publication date

1 January 2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Molecular Medicine

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1-2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

26-36

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Betulinic acid, a potent inhibitor of eukaryotic topoisomerase I: identification of the inhibitory step, the major functional group responsible and development of more potent derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Signal transduction pathways leading to cell cycle arrest and apoptosis induced by DNA topoisomerase poisons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

In vitro and in vivo Leishmanicidal activity of 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone (lapachol).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Experimental evaluation of second-line oral treatments of visceral leishmaniasis caused by Leishmania infantum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Trial of oral miltefosine for visceral leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Anti-AIDS agents--XXVII. Synthesis and anti-HIV activity of betulinic acid and dihydrobetulinic acid derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Activity of oral atovaquone alone and in combination with antimony in experimental visceral leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Antileishmanial activity of the ether phospholipid ilmofosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Antileishmanial activity of licochalcone A in mice infected with Leishmania major and in hamsters infected with Leishmania donovani

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Molecular and cytotoxic effects of camptothecin, a topoisomerase I inhibitor, on trypanosomes and Leishmania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Evidence for intercalation of chloroquine into DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

DNA topoisomerase poisons as antitumor drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

5 June 2018

Programmed cell death in the unicellular protozoan parasite Leishmania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

18 August 2018

Phase 2 trial of WR6026, an orally administered 8-aminoquinoline, in the treatment of visceral leishmaniasis caused by Leishmania chagasi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

18 August 2018

Activation of nuclear factor kappaB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

18 August 2018

The anti-leishmanial effect of Kalanchoe is mediated by nitric oxide intermediates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

18 August 2018

Drug-promoted cleavage of kinetoplast DNA minicircles. Evidence for type II topoisomerase activity in trypanosome mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1430381

18 August 2018

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medicinal plants in the fight against leishmaniasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual inhibition of DNA topoisomerases of Leishmania donovani by novel indolyl quinolines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decatenation of kinetoplast DNA by an ATP-dependent DNA topoisomerase from the kinetoplast hemoflagellate Leishmania donovani

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of itraconazole in the treatment of mucocutaneous leishmaniasis: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of bulk and c-myc P2 promoter-specific DNA damage by an anti-topoisomerase II agent salvicine is an early event leading to apoptosis in HL-60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular development of choleraphage phi 149 under permissive and nonpermissive conditions: an electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leishmania donovani: oral efficacy and toxicity of formycin B in the infected hamster

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diospyrin, a bisnaphthoquinone: a novel inhibitor of type I DNA topoisomerase of Leishmania donovani

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple procedure for the preparation of pure kinetoplast DNA network free of nuclear DNA from the kinetoplast hemoflagellate Leishmania donovani

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential actions of aclarubicin and doxorubicin: the role of topoisomerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/12765337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12765337%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q41872301&oldid=1899016504"