Down modulation of IFN-gamma signaling in alveolar macrophages isolated from smokers (Q41888499)

13 October 2017

Down modulation of IFN-gamma signaling in alveolar macrophages isolated from smokers (English)

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13 October 2017

Navneet K Dhillon

1

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13 October 2017

William J Murphy

2

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13 October 2017

Michael B Filla

3

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13 October 2017

Ana J Crespo

4

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13 October 2017

Heath A Latham

5

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13 October 2017

Amy O'Brien-Ladner

6

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13 October 2017

6 March 2009

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Toxicology and Applied Pharmacology

13 October 2017

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13 October 2017

237

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13 October 2017

1

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13 October 2017

22-28

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describes a project that uses

13 October 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2680937/fullTextXML

inferred from PubMed Central ID database lookup

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Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor.

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Interferon-gamma: biologic functions and HCV therapy (type I/II) (1 of 2 parts).

5 June 2018

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5 June 2018

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The role of IFN-gamma in immune responses to viral infections of the central nervous system

5 June 2018

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The potential for monocyte-mediated immunotherapy during infection and malignancy. Part I: apoptosis induction and cytotoxic mechanisms

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Mainstream and sidestream cigarette smoke condensates suppress macrophage responsiveness to interferon gamma

5 June 2018

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Differential regulation of human alveolar macrophage-derived interleukin-1beta and tumor necrosis factor-alpha by iron

5 June 2018

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Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes

5 June 2018

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Immunotoxicology of cigarette smoke condensates: suppression of macrophage responsiveness to interferon gamma

5 June 2018

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A family of cytokine-inducible inhibitors of signalling

5 June 2018

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The IFN gamma receptor: a paradigm for cytokine receptor signaling

5 June 2018

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The structure of the gene for the second chain of the human interferon-gamma receptor

5 June 2018

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Role of oxidants/antioxidants in smoking-induced lung diseases

5 June 2018

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IL-1 and tumor necrosis factor-alpha each up-regulate both the expression of IFN-gamma receptors and enhance IFN-gamma-induced HLA-DR expression on human monocytes and a human monocytic cell line (THP-1).

5 June 2018

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Priming of human monocytes for enhanced lipopolysaccharide responses: expression of alpha interferon, interferon regulatory factors, and tumor necrosis factor

5 June 2018

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The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

5 June 2018

1 reference

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Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)

5 June 2018

1 reference

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Inhaled recombinant interferon gamma in patients with lung cancer: pharmacokinetics and effects on chemiluminescence responses of alveolar macrophages and peripheral blood neutrophils and monocytes

5 June 2018

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The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors

5 June 2018

1 reference

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Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

5 June 2018

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Human alveolar macrophages: comparison of phagocytic ability, glucose utilization, and ultrastructure in smokers and nonsmokers

5 June 2018

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NHLBI workshop summary. Effects of tobacco smoke components on cellular and biochemical processes in the lung

5 June 2018

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Interferon-gamma, the activated macrophage, and host defense against microbial challenge

5 June 2018

1 reference

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Interleukin 1 production by alveolar macrophages is decreased in smokers

5 June 2018

1 reference

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Randomized phase II-III trial of combination beta and gamma interferons and etoposide and cisplatin in inoperable non-small cell cancer of the lung

5 June 2018

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Glycosylation of the human interferon-gamma receptor. N-linked carbohydrates contribute to structural heterogeneity and are required for ligand binding

5 June 2018

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The use of clonogenic assays in assessing the response of human lung cancer cell lines to alpha and gamma interferons alone or in combination with adriamycin

5 June 2018

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Developmental regulation of the cytokine repertoire in human macrophages: IL-1, IL-6, TNF-alpha, and M-CSF.

5 June 2018

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Lower respiratory tract iron burden is increased in association with cigarette smoking.

5 June 2018

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Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha

5 June 2018

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Tumor necrosis factor-alpha and IL-6 up-regulate IFN-gamma receptor gene expression in human monocytic THP-1 cells by transcriptional and post-transcriptional mechanisms

5 June 2018

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Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway.

5 June 2018

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The gene for the ligand binding chain of the human interferon gamma receptor.

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Non-heme (Fe3+) in the lung increases with age in both humans and rats

18 August 2018

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12 December 2020

Cigarette smoking decreases bioactive interleukin-6 secretion by alveolar macrophages

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12 December 2020

Intrapleural instillation of interferon gamma in patients with malignant pleurisy due to lung cancer

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12 December 2020

Role of recombinant interferon-gamma maintenance in responding patients with small cell lung cancer. A randomised phase III study of the EORTC Lung Cancer Cooperative Group

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12 December 2020

Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene

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12 December 2020

Comments on Role of recombinant interferon-gamma maintenance in responding patients with small cell lung cancer. A randomised phase III study of the EORTC Lung Cancer Cooperative Group, van Zandwijk et al., Eur J Cancer 1997, 33, 1759-1766

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12 December 2020

Ligand-independent down-regulation of IFN-gamma receptor 1 following TCR engagement

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12 December 2020

Expression of myeloid and major histocompatibility antigens on small cell carcinoma of the lung cell lines analyzed by cytofluorography: modulation by gamma-interferon

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12 December 2020

Gamma interferon priming of mouse and human macrophages for induction of tumor necrosis factor production by bacterial lipopolysaccharide

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12 December 2020

Colony inhibitory effect of recombinant human tumor necrosis factor (rH-TNF) and/or recombinant human interferon (rH-IFN)-alpha, -beta and -gamma on human lung cancer cell lines

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12 December 2020

Internalization and degradation of receptor-bound interferon-gamma by murine macrophages. Demonstration of receptor recycling

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12 December 2020

Differential examination of bronchoalveolar lavage cells in tobacco cigarette and marijuana smokers

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12 December 2020

Iron and ferritin contents and distribution in human alveolar macrophages

1 reference

12 December 2020

Cigarette smoking decreases interleukin 1 release by human alveolar macrophages

1 reference

12 December 2020

Release of tumor necrosis factor-alpha from human alveolar macrophages is decreased in smokers

1 reference

12 December 2020

Phase III trial of recombinant interferon gamma in complete responders with small-cell lung cancer

1 reference

12 December 2020

Modulation of the expression of the IFN-gamma receptor beta-chain controls responsiveness to IFN-gamma in human peripheral blood T cells

1 reference

12 December 2020

10.1016/J.TAAP.2009.02.021

Identifiers

DOI

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13 October 2017

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13 October 2017

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