The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection. (Q41894010)

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scientific article published on 2 October 2013

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English	The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection.	scientific article published on 2 October 2013

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26 February 2020

The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection (English)

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26 February 2020

Elizabeth Sloan

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26 February 2020

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Delphine Cuchet-Lourenço

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26 February 2020

Gail Anderson

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26 February 2020

Anne Orr

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26 February 2020

Roger D Everett

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26 February 2020

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2 October 2013

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26 February 2020

Journal of Virology

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26 February 2020

87

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26 February 2020

24

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26 February 2020

13422-13432

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26 February 2020

Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells

1 reference

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5 June 2018

Herpes simplex virus 1 infection induces activation and subsequent inhibition of the IFI16 and NLRP3 inflammasomes

1 reference

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5 June 2018

Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes.

1 reference

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5 June 2018

Regulation of alphaherpesvirus infections by the ICP0 family of proteins

1 reference

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5 June 2018

The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71

1 reference

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5 June 2018

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

1 reference

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5 June 2018

Herpes simplex virus 1 ubiquitin ligase ICP0 interacts with PML isoform I and induces its SUMO-independent degradation.

1 reference

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5 June 2018

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

1 reference

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5 June 2018

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

1 reference

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5 June 2018

The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication

1 reference

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5 June 2018

Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localization

1 reference

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5 June 2018

A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence

1 reference

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The PYHIN protein family as mediators of host defenses.

1 reference

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5 June 2018

SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes

1 reference

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5 June 2018

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

1 reference

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5 June 2018

IFI16 is an innate immune sensor for intracellular DNA

1 reference

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5 June 2018

Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx

1 reference

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5 June 2018

Analysis of the functions of herpes simplex virus type 1 regulatory protein ICP0 that are critical for lytic infection and derepression of quiescent viral genomes

1 reference

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5 June 2018

STAT-1- and IRF-3-dependent pathways are not essential for repression of ICP0-null mutant herpes simplex virus type 1 in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838218

5 June 2018

Replication of ICP0-null mutant herpes simplex virus type 1 is restricted by both PML and Sp100.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838218

5 June 2018

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

1 reference

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5 June 2018

Herpes simplex virus type 1 genomes are associated with ND10 nuclear substructures in quiescently infected human fibroblasts

1 reference

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5 June 2018

PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0

1 reference

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The HIN-200 family: more than interferon-inducible genes?

1 reference

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5 June 2018

ND10 components relocate to sites associated with herpes simplex virus type 1 nucleoprotein complexes during virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838218

5 June 2018

Human cytomegalovirus tegument protein pp71 directs long-term gene expression from quiescent herpes simplex virus genomes

1 reference

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5 June 2018

Herpes simplex virus type 1 regulatory protein ICP0 does not protect cyclins D1 and D3 from degradation during infection

1 reference

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5 June 2018

Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0.

1 reference

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5 June 2018

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

1 reference

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Recruitment of herpes simplex virus type 1 transcriptional regulatory protein ICP4 into foci juxtaposed to ND10 in live, infected cells

1 reference

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Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16

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5 June 2018

The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms

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5 June 2018

Quiescent viral genomes in human fibroblasts after infection with herpes simplex virus type 1 Vmw65 mutants

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5 June 2018

Separation of sequence requirements for HSV-1 Vmw110 multimerisation and interaction with a 135-kDa cellular protein

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5 June 2018

An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1

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5 June 2018

Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110.

1 reference

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5 June 2018

Construction and characterization of herpes simplex virus type 1 mutants with defined lesions in immediate early gene 1.

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5 June 2018

A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

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5 June 2018

The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0.

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Innate DNA sensing moves to the nucleus

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12 December 2020

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10.1128/JVI.02474-13

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26 February 2020

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26 February 2020

1 reference

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26 February 2020

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