Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection (Q41896864)

13 October 2017

Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection (English)

1 reference

13 October 2017

1 reference

Esteban Domingo Solans

series ordinal

4

1 reference

13 October 2017

5

1 reference

13 October 2017

Héctor Moreno

1

1 reference

13 October 2017

Héctor Tejero

series ordinal

2

1 reference

13 October 2017

Juan Carlos de la Torre

series ordinal

3

1 reference

13 October 2017

language of work or name

English

0 references

publication date

19 March 2012

1 reference

13 October 2017

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13 October 2017

7

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13 October 2017

3

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13 October 2017

e32550

1 reference

Creative Commons Attribution 4.0 International

13 October 2017

start time

19 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Lethal Mutagenesis: Targeting the Mutator Phenotype in Cancer

5 June 2018

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A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

5 June 2018

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Quasispecies theory and the behavior of RNA viruses

5 June 2018

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Pathways to extinction: beyond the error threshold

5 June 2018

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5 June 2018

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Competition-colonization dynamics in an RNA virus

5 June 2018

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Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays

5 June 2018

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Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections

5 June 2018

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Therapeutically targeting RNA viruses via lethal mutagenesis

5 June 2018

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Arenavirus genetic diversity and its biological implications

5 June 2018

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Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

5 June 2018

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Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

5 June 2018

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Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.

5 June 2018

1 reference

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No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus

5 June 2018

1 reference

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Superinfection exclusion in BHK-21 cells persistently infected with Junín virus

5 June 2018

1 reference

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Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants

5 June 2018

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Transmission of lymphocytic choriomeningitis virus by organ transplantation

5 June 2018

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Historical Lassa fever reports and 30-year clinical update

5 June 2018

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5 June 2018

What is a quasispecies?

1 reference

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Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

5 June 2018

1 reference

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Quasispecies theory in the context of population genetics

5 June 2018

1 reference

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Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Suppression of viral infectivity through lethal defection

5 June 2018

1 reference

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Arenavirus extinction through lethal mutagenesis

5 June 2018

1 reference

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Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus.

5 June 2018

1 reference

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Viral error catastrophe by mutagenic nucleosides

5 June 2018

1 reference

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Evolutionary transition toward defective RNAs that are infectious by complementation.

5 June 2018

1 reference

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Preextinction viral RNA can interfere with infectivity

5 June 2018

1 reference

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Resistance to superinfection of Vero cells persistently infected with Junin virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

The small RING finger protein Z drives arenavirus budding: Implications for antiviral strategies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Mutagenesis versus Inhibition in the Efficiency of Extinction of Foot-and-Mouth Disease Virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV).

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Human infection with arenaviruses in the Americas.

5 June 2018

1 reference

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Arenaviruses: genomic RNAs, transcription, and replication

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Transcription and RNA replication of tacaribe virus genome and antigenome analogs require N and L proteins: Z protein is an inhibitor of these processes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Efficient Virus Extinction by Combinations of a Mutagen and Antiviral Inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Mutation rates among RNA viruses

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Genetic lesions associated with Muller's ratchet in an RNA virus.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Long-term, large-population passage of aphthovirus can generate and amplify defective noninterfering particles deleted in the leader protease gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Rapid evolution of RNA genomes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Autointerference of Marituba Virus (Bunyaviridae) in mouse L cells by defective interfering particles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Defective Viral Particles and Viral Disease Processes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Selforganization of matter and the evolution of biological macromolecules

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Properties of Defective Lymphocytic Choriomeningitis Virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Cyclic production of vesicular stomatitis virus caused by defective interfering particles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Defective interfering viruses

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Defective interfering particles of poliovirus. 3. Interference and enrichment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Polysomal ribonucleic acid of vesicular stomatitis virus-infected HeLa cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Genetic characteristics of conditional lethal mutants of vesicular stomatitis virus induced by 5-fluorouracil, 5-azacytidine, and ethyl methane sulfonate

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Host cell-dependent homologous interference in lymphocytic choriomeningitis virus infection

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Analysis of the genomic L RNA segment from lymphocytic choriomeningitis virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Establishment of cell lines persistently infected with foot-and-mouth disease virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Characterization of virulent isolates of vesicular stomatitis virus in relation to interference by defective particles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Delayed formation of defective interfering particles in vesicular stomatitis virus-infected cells: kinetic studies of viral protein and RNA synthesis during autointerference.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Detection of virus-specific RNA-dependent RNA polymerase activity in extracts from cells infected with lymphocytic choriomeningitis virus: in vitro synthesis of full-length viral RNA species.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Effects of defective interfering viruses on virus replication and pathogenesis in vitro and in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Biochemical and immunological evidence that the 11 kDa zinc-binding protein of lymphocytic choriomeningitis virus is a structural component of the virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Sequence and structural elements that contribute to efficient encephalomyocarditis virus RNA translation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Homologous interference of lymphocytic choriomeningitis virus: detection and measurement of interference focus-forming units

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Nucleotide sequence heterogeneity of an RNA phage population.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Defective interfering (di) particles of poliovirus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Full-length genome analysis of natural isolates of vesicular stomatitis virus (Indiana 1 serotype) from North, Central and South America

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth-disease virus

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307711

Mutant spectra in virus behavior

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032550

Infection of mouse fibroblasts by cardioviruses: Premature uncoating and its prevention by elevated pH and magnesium chloride

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22442668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Generation of defective interfering particles in picornaviruses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22442668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Determinants of lymphocytic choriomeningitis interference

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22442668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0032550

1 reference

13 October 2017

0 references

1 reference

13 October 2017

PubMed publication ID

22442668

1 reference