Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord. (Q41899271)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24918341%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord (English)

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20 March 2020

7

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20 March 2020

author name string

Hong Z Yin

1

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20 March 2020

Stephen Yu

2

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20 March 2020

Cheng-I Hsu

3

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20 March 2020

Joe Liu

4

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20 March 2020

Allan Acab

5

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20 March 2020

Richard Wu

6

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20 March 2020

Benjamin J Chiang

8

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20 March 2020

John H Weiss

9

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20 March 2020

language of work or name

English

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publication date

8 June 2014

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20 March 2020

published in

Experimental Neurology

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20 March 2020

volume

261

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20 March 2020

page(s)

1-9

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The non-protein amino acid BMAA is misincorporated into human proteins in place of L-serine causing protein misfolding and aggregation

20 March 2020

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1 reference

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Cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) in shark fins

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Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane

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Animal models of BMAA neurotoxicity: a critical review

5 June 2018

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Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS.

5 June 2018

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Beta-N-methylamino-L-alanine enhances neurotoxicity through multiple mechanisms

5 June 2018

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

5 June 2018

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BMAA selectively injures motor neurons via AMPA/kainate receptor activation

5 June 2018

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Mitochondrial dysfunction and its role in motor neuron degeneration in ALS.

5 June 2018

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Diverse taxa of cyanobacteria produce β-N-methylamino-l-alanine, a neurotoxic amino acid

5 June 2018

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Occurrence of beta-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam

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A mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam

5 June 2018

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Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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In vitro kainate injury to large, SMI-32(+) spinal neurons is Ca2+ dependent.

5 June 2018

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5 June 2018

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An appraisal of the neurotoxicity of cycad and the etiology of amyotrophic lateral sclerosis on Guam

5 June 2018

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Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

5 June 2018

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Guam ALS/parkinsonism-dementia: a long-latency neurotoxic disorder caused by "slow toxin(s)" in food?

5 June 2018

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Beta-N-methylamino-L-alanine neurotoxicity: requirement for bicarbonate as a cofactor

5 June 2018

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Specific antagonism of excitotoxic action of 'uncommon' amino acids assayed in organotypic mouse cortical cultures

5 June 2018

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5 June 2018

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5 June 2018

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Neurotoxicity of beta-N-methylamino-L-alanine (BMAA) and beta-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons

5 June 2018

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2-Amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: an unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam.

5 June 2018

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5 June 2018

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5 June 2018

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Cerebral uptake and protein incorporation of cyanobacterial toxin β-N-methylamino-L-alanine

5 June 2018

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18 August 2018

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18 August 2018

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18 August 2018

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Co-occurrence of beta-N-methylamino-L-alanine, a neurotoxic amino acid with other cyanobacterial toxins in British waterbodies, 1990-2004.

18 August 2018

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18 August 2018

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18 August 2018

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Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

18 August 2018

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Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro

18 August 2018

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Interaction between beta-N-methylamino-L-alanine and excitatory amino acid receptors in brain slices and neuronal cultures.

18 August 2018

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Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms

18 August 2018

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Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS

3 November 2018

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AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability

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Neuroactive carbamate adducts of beta-N-methylamino-L-alanine and ethylenediamine. Detection and quantitation under physiological conditions by 13C NMR

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Determination of beta-N-methylamino-L-alanine (BMAA) in plant (Cycas circinalis L.) and animal tissue by precolumn derivatization with 9-fluorenylmethyl chloroformate (FMOC) and reversed-phase high-performance liquid chromatography

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Identifiers

DOI

1 reference

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release_flhravg3evhtthlv2putnne3we

20 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/flhravg3evhtthlv2putnne3we

24 November 2022

mapped directly with Wikidata item

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20 March 2020

PubMed publication ID

24918341

1 reference

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