Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping (Q41906651)

13 October 2017

Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping (English)

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13 October 2017

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Meiping Chang

1

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13 October 2017

Sarah Smith

2

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13 October 2017

Andrew Thorpe

3

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13 October 2017

Michael J Barratt

4

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13 October 2017

Farzana Karim

5

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13 October 2017

language of work or name

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16 September 2010

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13 October 2017

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13 October 2017

6

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13 October 2017

56

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https://scigraph.springernature.com/pub.10.1186/1744-8069-6-56

13 October 2017

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Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

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Photoreceptor protection by adeno-associated virus-mediated LEDGF expression in the RCS rat model of retinal degeneration: probing the mechanism

5 June 2018

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5 June 2018

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A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritis

5 June 2018

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Muscarinic acetylcholine receptors: new potential therapeutic targets in antinociception and in cancer therapy

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Inhibition of interleukin-1beta-induced group IIA secretory phospholipase A2 expression by peroxisome proliferator-activated receptors (PPARs) in rat vascular smooth muscle cells: cooperation between PPARbeta and the proto-oncogene BCL-6

5 June 2018

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Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord.

5 June 2018

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Pathophysiology of peripheral neuropathic pain: immune cells and molecules.

5 June 2018

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Rhythmic pattern in pain and their chronotherapy

5 June 2018

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Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses

5 June 2018

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The endocannabinoid pathway in Huntington's disease: a comparison with other neurodegenerative diseases

5 June 2018

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Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms

5 June 2018

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

5 June 2018

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Robust increase of cutaneous sensitivity, cytokine production and sympathetic sprouting in rats with localized inflammatory irritation of the spinal ganglia

5 June 2018

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The BTB domain of the nuclear matrix protein NRP/B is required for neurite outgrowth

5 June 2018

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Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation

5 June 2018

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Plasticity of gene expression in injured human dorsal root ganglia revealed by GeneChip oligonucleotide microarrays

5 June 2018

1 reference

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A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

5 June 2018

1 reference

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Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

CCR5 mediates Fas- and caspase-8 dependent apoptosis of both uninfected and HIV infected primary human CD4 T cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Phenoxybenzamine binding reveals the helical orientation of the third transmembrane domain of adrenergic receptors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Differential requirement of the cytoplasmic subregions of gamma c chain in T cell development and function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Multiple roles for hepatocyte growth factor in sympathetic neuron development.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons.

5 June 2018

1 reference

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Efficient analysis of experimental observations.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949723

Phenoxybenzamine in the treatment of causalgia. Report of 40 cases

5 June 2018

1 reference

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Alpha adrenergic blocking agents: anti-nociceptive activity and enhancement of morphine-induced analgesia.

5 June 2018

1 reference

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Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds

5 June 2018

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Gene expression profile of dorsal root ganglion in a lumbar radiculopathy model

5 June 2018

1 reference

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Treatment of complex regional pain syndrome type I with oral phenoxybenzamine: rationale and case reports

18 August 2018

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Peripheral inflammation increases Scya2 expression in sensory ganglia and cytokine and endothelial related gene expression in inflamed tissue

18 August 2018

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Depletion of vesicular zinc in dorsal horn of spinal cord causes increased neuropathic pain in mice.

18 August 2018

1 reference

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Comparison of gene expression profiles in neuropathic and inflammatory pain.

18 August 2018

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18 August 2018

1 reference

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CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis

18 August 2018

1 reference

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Antagonism of the frequency of phenylquinone-induced writhing in the mouse by weak analgesics and nonanalgesics

18 August 2018

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Agonist—antagonist properties of phenoxybenzamine in antinociception and opiate dependence tests

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Finasteride, a 5alpha-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat

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Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells

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Identifiers

DOI

10.1186/1744-8069-6-56

1 reference

Dimensions Publication ID

13 October 2017

0 references

1 reference

13 October 2017

1 reference