Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration (Q41916686)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25475538%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration (English)

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24 February 2020

0 references

4

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24 February 2020

Sidney Strickland

5

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24 February 2020

author name string

Marta Cortes-Canteli

1

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24 February 2020

Larissa Mattei

2

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24 February 2020

Allison T Richards

3

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24 February 2020

publication date

31 October 2014

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24 February 2020

published in

Neurobiology of Aging

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24 February 2020

volume

36

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24 February 2020

issue

2

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24 February 2020

page(s)

608-617

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Are blood-based protein biomarkers for Alzheimer's disease also involved in other brain disorders? A systematic review

24 February 2020

cites work

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Fibrinogen and altered hemostasis in Alzheimer's disease

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Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid

5 June 2018

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Fibrinogen as a key regulator of inflammation in disease

5 June 2018

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Effects of hypoperfusion in Alzheimer's disease

5 June 2018

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Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy

5 June 2018

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Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

5 June 2018

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Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease?

5 June 2018

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Primary cerebral blood flow deficiency and Alzheimer's disease: shadows and lights

5 June 2018

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Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.

5 June 2018

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Neuron loss in transgenic mouse models of Alzheimer's disease

5 June 2018

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The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

5 June 2018

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Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

5 June 2018

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Age-dependent increase in lysosome-associated membrane protein 1 and early-onset behavioral deficits in APPSL transgenic mouse model of Alzheimer's disease.

5 June 2018

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5 June 2018

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Classification and basic pathology of Alzheimer disease

5 June 2018

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A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain

5 June 2018

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Alzheimer disease models and human neuropathology: similarities and differences

5 June 2018

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Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease

5 June 2018

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The hunt for dying neurons: insight into the neuronal loss in Alzheimer's disease

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Fibrinogen and fibrin structure and functions

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Subicular Dendritic Arborization in Alzheimer's Disease Correlates with Neurofibrillary Tangle Density

5 June 2018

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Alzheimer disease as a vascular disorder: nosological evidence

5 June 2018

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Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains

5 June 2018

1 reference

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Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background

5 June 2018

1 reference

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

5 June 2018

1 reference

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Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease.

5 June 2018

1 reference

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Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression.

18 August 2018

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Contrast-enhanced magnetic resonance microangiography reveals remodeling of the cerebral microvasculature in transgenic ArcAβ mice.

18 August 2018

1 reference

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Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: a study in the MRC-CFAS population neuropathology cohort.

18 August 2018

1 reference

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Converging perturbed microvasculature and microglial clusters characterize Alzheimer disease brain.

18 August 2018

1 reference

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Dystrophic neurites of senile plaques in Alzheimer's disease are deficient in cytochrome c oxidase.

18 August 2018

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Plasma fibrinogen is associated with cognitive decline and risk for dementia in patients with mild cognitive impairment.

18 August 2018

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New insight into Alzheimer disease: demonstration of fibrin(ogen)-serum albumin insoluble deposits in brain tissue.

18 August 2018

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Microvascular pathology in the aging human brain: evidence that senile plaques are sites of microhaemorrhages.

18 August 2018

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Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease.

18 August 2018

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Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia.

18 August 2018

1 reference

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Pericapillary haem-rich deposits: evidence for microhaemorrhages in aging human cerebral cortex.

18 August 2018

1 reference

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Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

18 August 2018

1 reference

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The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration.

18 August 2018

1 reference

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Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier.

18 August 2018

1 reference

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

18 August 2018

1 reference

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Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

18 August 2018

1 reference

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Synaptic and neuritic alterations during the progression of Alzheimer's disease

18 August 2018

1 reference

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Inflammation and Alzheimer's disease

18 August 2018

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PubMed

12 December 2020

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12 December 2020

Monoclonal antibodies to a synthetic fibrin-like peptide bind to human fibrin but not fibrinogen

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PubMed

12 December 2020

Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice

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PubMed

12 December 2020

10.1016/J.NEUROBIOLAGING.2014.10.030

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25475538%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25475538%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25475538%20AND%20SRC:MED&resulttype=core&format=json