Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. (Q41933726)

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21 January 2020

title

Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase (English)

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frontotemporal lobar degeneration

21 January 2020

main subject

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2

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21 January 2020

Nathalie Brouwers

4

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21 January 2020

Dorothee Dormann

14

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Christine Van Broeckhoven

21 January 2020

18

object named as

Christine Van Broeckhoven

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21 January 2020

17

Jochen Herms

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21 January 2020

author name string

Katrin Fellerer

3

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21 January 2020

Michael Willem

5

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21 January 2020

Sven Lammich

6

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21 January 2020

Ilse Gijselinck

7

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21 January 2020

Tobias Bittner

8

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21 January 2020

Aaron M Carlson

9

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21 January 2020

Florenz Sasse

10

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21 January 2020

Brigitte Kunze

11

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21 January 2020

Heinrich Steinmetz

12

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21 January 2020

Rolf Jansen

13

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21 January 2020

Marc Cruts

16

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21 January 2020

Anja Capell

1

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21 January 2020

Kristel Sleegers

15

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21 January 2020

Christian Haass

19

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21 January 2020

language of work or name

English

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publication date

1 February 2011

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21 January 2020

published in

Journal of Neuroscience

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21 January 2020

volume

31

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21 January 2020

issue

5

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21 January 2020

page(s)

1885-1894

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Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

21 January 2020

cites work

1 reference

12 December 2020

Bepridil. A review of its pharmacological properties and therapeutic use in stable angina pectoris

1 reference

12 December 2020

Amiodarone: guidelines for use and monitoring

1 reference

12 December 2020

Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region

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12 December 2020

The bafilomycin/concanamycin binding site in subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae

1 reference

12 December 2020

Archazolid and apicularen: novel specific V-ATPase inhibitors

1 reference

12 December 2020

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

1 reference

12 December 2020

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

1 reference

12 December 2020

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

12 December 2020

Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes

1 reference

12 December 2020

Frontotemporal dementia.

1 reference

12 December 2020

Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia.

1 reference

12 December 2020

Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes

1 reference

12 December 2020

Amiodarone and bepridil inhibit anthrax toxin entry into host cells

1 reference

12 December 2020

Immunohistochemical demonstration of the distribution of chloroquine (CQ) and its metabolites in CQ-poisoned mice

1 reference

12 December 2020

Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene.

1 reference

12 December 2020

The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments

1 reference

12 December 2020

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

1 reference

12 December 2020

Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family.

1 reference

12 December 2020

Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion.

1 reference

12 December 2020

Targeting vacuolar H+-ATPases as a new strategy against cancer

1 reference

12 December 2020

Progranulin is a stress-response factor in fibroblasts subjected to hypoxia and acidosis

1 reference

12 December 2020

Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia

1 reference

12 December 2020

Organotypic entorhino-hippocampal slice cultures--a tool to study the molecular and cellular regulation of axonal regeneration and collateral sprouting in vitro

1 reference

12 December 2020

Loss of progranulin function in frontotemporal lobar degeneration

1 reference

12 December 2020

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

1 reference

12 December 2020

Granulin mutations associated with frontotemporal lobar degeneration and related disorders: an update

1 reference

12 December 2020

Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease

1 reference

12 December 2020

Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin

1 reference

12 December 2020

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration.

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12 December 2020

Inhibitors of V-ATPases: old and new players

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12 December 2020

Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members

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12 December 2020

Serum biomarker for progranulin-associated frontotemporal lobar degeneration

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12 December 2020

A gene network regulating lysosomal biogenesis and function

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12 December 2020

A new subtype of frontotemporal lobar degeneration with FUS pathology

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12 December 2020

The granulin gene family: from cancer to dementia

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12 December 2020

Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies

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12 December 2020

Progranulin is expressed within motor neurons and promotes neuronal cell survival

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12 December 2020

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

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12 December 2020

The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein

1 reference

12 December 2020

Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.

1 reference

12 December 2020

The dynamic nature of the Golgi complex

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12 December 2020

Pharmacokinetics of amiodarone in rats

1 reference

12 December 2020

10.1523/JNEUROSCI.5757-10.2011

Identifiers

DOI

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21 January 2020

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