Novel antimalarial aminoquinolines: heme binding and effects on normal or Plasmodium falciparum-parasitized human erythrocytes. (Q41937826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19651905%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Novel antimalarial aminoquinolines: heme binding and effects on normal or Plasmodium falciparum-parasitized human erythrocytes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19651905%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

main subject

antimalarial

0 references

Plasmodium falciparum

1 reference

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19651905%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Donatella Taramelli

6

1 reference

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4 February 2020

author name string

Fausta Omodeo-Salè

1

1 reference

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4 February 2020

Lucia Cortelezzi

2

1 reference

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4 February 2020

Nicoletta Basilico

3

1 reference

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4 February 2020

Manolo Casagrande

4

1 reference

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4 February 2020

language of work or name

English

0 references

publication date

3 August 2009

1 reference

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Antimicrobial Agents and Chemotherapy

4 February 2020

published in

1 reference

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4 February 2020

volume

53

1 reference

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4 February 2020

issue

10

1 reference

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4 February 2020

page(s)

4339-4344

1 reference

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Evidence of Artemisinin-Resistant Malaria in Western Cambodia

4 February 2020

cites work

1 reference

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Two complementary fluorimetric assays for the determination of aminoquinoline binding and uptake by human erythrocytes in vitro

5 June 2018

1 reference

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Efficacy and safety of artemisinin-based antimalarial in the treatment of uncomplicated malaria in children in southern Tanzania

5 June 2018

1 reference

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Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum. Role of beta-haematin inhibition and drug concentration in vacuolar water- and lipid-phases.

5 June 2018

1 reference

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The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization.

5 June 2018

1 reference

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PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.

5 June 2018

1 reference

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Accelerated denaturation of hemoglobin and the antimalarial action of chloroquine

5 June 2018

1 reference

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A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.

5 June 2018

1 reference

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Interactions of quinoline antimalarials with hematin in solution

5 June 2018

1 reference

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Quinolines and artemisinin: chemistry, biology and history.

5 June 2018

1 reference

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4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity

5 June 2018

1 reference

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Antimalarial drug resistance

5 June 2018

1 reference

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Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites.

5 June 2018

1 reference

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Antimalarial 9-anilinoacridine compounds directed at hematin

5 June 2018

1 reference

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The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids

5 June 2018

1 reference

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COMPLEX FORMATION BETWEEN CHLOROQUINE AND FERRIHAEMIC ACID IN VITRO, AND ITS EFFECT ON THE ANTIMALARIAL ACTION OF CHLOROQUINE.

5 June 2018

1 reference

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Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Chloroquine-resistant malaria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Mechanism of malarial haem detoxification inhibition by chloroquine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Standardization of the physicochemical parameters to assess in vitro the beta-hematin inhibitory activity of antimalarial drugs.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

The structure of malaria pigment beta-haematin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinoline-hematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

On the molecular mechanism of chloroquine's antimalarial action

5 June 2018

1 reference

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Quinoline anti-malarial drugs inhibit spontaneous formation of beta-haematin (malaria pigment).

5 June 2018

1 reference

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Mechanism of hemolysis induced by ferriprotoporphyrin IX.

5 June 2018

1 reference

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The effect of ferriprotoporphyrin IX and chloroquine on phospholipid monolayers and the possible implications to antimalarial activity

5 June 2018

1 reference

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Diverse membrane-active agents modify the hemolytic response to ferriprotoporphyrin IX.

5 June 2018

1 reference

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Preparation and antileukemic activity of quinolizidinylalkyl-derivatives of 4-aminoquinoline and 9-aminoacridine

5 June 2018

1 reference

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Haemozoin (beta-haematin) biomineralization occurs by self-assembly near the lipid/water interface

5 June 2018

1 reference

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Destabilisation and subsequent lysis of human erythrocytes induced by Plasmodium falciparum haem products

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764181

Ca replacement by cationic amphiphilic drugs from lipid monolayers

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19651905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.00536-09

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19651905%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19651905%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

19651905

1 reference