Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis (Q41946219)

14 October 2017

Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis (English)

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14 October 2017

transmembrane protein

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author name string

A Hameed

1

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14 October 2017

K J Olsen

2

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14 October 2017

M K Lee

3

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14 October 2017

M G Lichtenheld

4

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14 October 2017

E R Podack

5

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14 October 2017

language of work or name

English

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publication date

1 March 1989

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Journal of Experimental Medicine

14 October 2017

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14 October 2017

169

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14 October 2017

3

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14 October 2017

765-777

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Cell death: the significance of apoptosis

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Staphylococcal alpha-toxin: oligomerization of hydrophilic monomers to form amphiphilic hexamers induced through contact with deoxycholate detergent micelles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

DNA degradation in mammalian cells following complement-mediated cytolysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Mechanism of cytotoxicity of human large granular lymphocytes: relationship of the cytotoxic lymphocyte protein to the ninth component (C9) of human complement

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Structure and function of human perforin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Homology of perforin to the ninth component of complement (C9).

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Cell-mediated and glucocorticoid-mediated target cell lysis do not appear to share common pathways.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

DNA of human Raji target cells is damaged upon lymphocyte-mediated lysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

DNA fragmentation: manifestation of target cell destruction mediated by cytotoxic T-cell lines, lymphotoxin-secreting helper T-cell clones, and cell-free lymphotoxin-containing supernatant

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Cloning and expression of murine lymphotoxin cDNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Cytotoxic granules from killer cells: specificity of granules and insertion of channels of defined size into target membranes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189290

Elimination of terminal complement intermediates from the plasma membrane of nucleated cells: the rate of disappearance differs for cells carrying C5b-7 or C5b-8 or a mixture of C5b-8 with a limited number of C5b-9

18 August 2018

1 reference

12 December 2020

A comparison of lysis mediated by Lyt 2+ TNP-specific cytotoxic-T-lymphocyte (CTL) lines with that mediated by rapidly internalized lymphotoxin-containing supernatant fluids: evidence for a role of soluble mediators in CTL-mediated killing

1 reference

12 December 2020

Differences in target cell DNA fragmentation induced by mouse cytotoxic T lymphocytes and natural killer cells

1 reference

12 December 2020

The degree of CTL-induced DNA solubilization is not determined by the human vs mouse origin of the target cell

1 reference

12 December 2020

Increased cytotoxicity and CD16 (Leu 11) expression in long-term, IL-2-activated human peripheral blood mononuclear cells

1 reference

12 December 2020

The role of Ca2+ in activation of mature cytotoxic T lymphocytes for lysis

1 reference

12 December 2020

Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity

1 reference

12 December 2020

Isolation and characterization of cytotoxic granules from human lymphokine (interleukin 2) activated killer cells

1 reference

12 December 2020

Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement

1 reference

12 December 2020

Mechanisms of immune lysis. II. CTL-induced nuclear disintegration of the target begins within minutes of cell contact

1 reference

12 December 2020

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

1 reference

12 December 2020

A novel serine esterase expressed by cytotoxic T lymphocytes

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12 December 2020

Identifiers

DOI

10.1084/JEM.169.3.765

1 reference

14 October 2017

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14 October 2017

PubMed publication ID

2538546

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