New furin inhibitors based on weakly basic amidinohydrazones (Q41956540)

14 October 2017

New furin inhibitors based on weakly basic amidinohydrazones (English)

1 reference

14 October 2017

Frank Sielaff

1

1 reference

14 October 2017

Manuel E Than

2

1 reference

14 October 2017

Dorian Bevec

3

1 reference

14 October 2017

Iris Lindberg

4

1 reference

14 October 2017

Torsten Steinmetzer

5

1 reference

14 October 2017

language of work or name

English

0 references

publication date

25 November 2010

1 reference

Bioorganic & Medicinal Chemistry Letters

14 October 2017

1 reference

14 October 2017

21

1 reference

14 October 2017

2

1 reference

14 October 2017

836-840

1 reference

Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Inhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Inhibitors of proprotein convertases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

The vagus nerve and the nicotinic anti-inflammatory pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Furin at the cutting edge: from protein traffic to embryogenesis and disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Trypanocidal 1,3-arylene diketone bis(guanylhydrazone)s. Structure-activity relationships among substituted and heterocyclic analogues

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4737580

2,6-Dichlorobenzylidene amino guanidine acetate (Wy-8678). A new hypotensive agent

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21168329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis of tight binding inhibitors and their action on the proprotein-processing enzyme furin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21168329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amidinohydrazones as guanidine bioisosteres: application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21168329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2010.11.092

1 reference

14 October 2017

1 reference

14 October 2017

1 reference