LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. (Q41978713)

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scientific article published on July 2013

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English	LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program.	scientific article published on July 2013

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5 March 2020

LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program (English)

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5 March 2020

neural stem cell

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1

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5 March 2020

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5 March 2020

Charles G Eberhart

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Charles G Eberhart

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5 March 2020

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Marianne Hütt-Cabezas

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5 March 2020

Brent A Orr

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5 March 2020

Melanie Weingart

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5 March 2020

Isabella Taylor

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5 March 2020

Anand K D Rajan

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5 March 2020

Yazmin Odia

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5 March 2020

Ulf Kahlert

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5 March 2020

Jarek Maciaczyk

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5 March 2020

Guido Nikkhah

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5 March 2020

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1 July 2013

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5 March 2020

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5 March 2020

4

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5 March 2020

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5 March 2020

1050-1064

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5 March 2020

Positive expression of Lin28 is correlated with poor survival in gastric carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Lin28 regulates HER2 and promotes malignancy through multiple mechanisms

1 reference

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Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis

1 reference

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5 June 2018

MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth

1 reference

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5 June 2018

Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transition

1 reference

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5 June 2018

Sequential activation of Snail1 and N-Myc modulates sonic hedgehog-induced transformation of neural cells

1 reference

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5 June 2018

BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.

1 reference

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5 June 2018

c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.

1 reference

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5 June 2018

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

1 reference

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5 June 2018

LIN28B promotes colon cancer progression and metastasis

1 reference

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5 June 2018

SNAI1 is involved in the proliferation and migration of glioblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes

1 reference

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5 June 2018

The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Let-7 microRNA inhibits the proliferation of human glioblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

SNAI2/Slug promotes growth and invasion in human gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

A role for Lin28 in primordial germ-cell development and germ-cell malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Lin28 promotes transformation and is associated with advanced human malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development

1 reference

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5 June 2018

HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells

1 reference

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5 June 2018

Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

Identification of let-7-regulated oncofetal genes

1 reference

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5 June 2018

Suppression of non-small cell lung tumor development by the let-7 microRNA family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759665

5 June 2018

let-7 regulates self renewal and tumorigenicity of breast cancer cells

1 reference

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5 June 2018

Induced pluripotent stem cell lines derived from human somatic cells

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A common variant of HMGA2 is associated with adult and childhood height in the general population

1 reference

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1 reference

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Prevalence and functional consequence of PHOX2B mutations in neuroblastoma.

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Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.

1 reference

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Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 gene mutations in pediatric brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical expression of embryonic stem cell markers in malignant rhabdoid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23846349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.18632/ONCOTARGET.1131

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23846349%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PMC publication ID

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5 March 2020

PubMed publication ID

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5 March 2020

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