Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons. (Q41981569)

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scientific article published on 9 April 2012

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English	Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.	scientific article published on 9 April 2012

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scholarly article

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28 January 2020

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons (English)

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Jillian C Belrose

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Lynn J Gierszewski

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John F MacDonald

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Michael F Jackson

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publication date

9 April 2012

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Molecular Brain

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0 references

Dependence of NMDA/GSK-3β mediated metaplasticity on TRPM2 channels at hippocampal CA3-CA1 synapses

1 reference

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5 June 2018

Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat.

1 reference

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5 June 2018

Glutathione restores the mechanism of synaptic plasticity in aged mice to that of the adult.

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5 June 2018

Roles of TRPM2 in oxidative stress

1 reference

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5 June 2018

Sex differences in neuroprotection provided by inhibition of TRPM2 channels following experimental stroke.

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Endogenous amyloidogenesis in long-term rat hippocampal cell cultures.

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5 June 2018

TRPM2: a multifunctional ion channel for calcium signalling.

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Selective neuronal vulnerability to oxidative stress in the brain

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Regulation of neuronal glutathione synthesis

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5 June 2018

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Effects of age and caloric intake on glutathione redox state in different brain regions of C57BL/6 and DBA/2 mice

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Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

1 reference

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Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y.

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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

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Age-related changes of glutathione content, glucose transport and metabolism, and mitochondrial electron transfer function in mouse brain

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Modulation of glutamate receptor functions by glutathione

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Reduced glutathione inhibits beta-NAD+-activated non-selective cation currents in the CRI-G1 rat insulin-secreting cell line

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5 June 2018

Multiple roles of glutathione in the central nervous system.

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Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

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18 August 2018

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18 August 2018

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1 reference

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The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid

1 reference

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12 December 2020

based on heuristic

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Glutathione modulates Ca(2+) influx and oxidative toxicity through TRPM2 channel in rat dorsal root ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22487454

12 December 2020

based on heuristic

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N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22487454

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of aging on glutathione and cysteine levels in different regions of the mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22487454

12 December 2020

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Amyloid beta-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione: an overview of biosynthesis and modulation

1 reference

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12 December 2020

based on heuristic

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The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation

1 reference

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12 December 2020

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A cell-survival factor (N-acetyl-L-cysteine) alters the in vivo fate of constitutively proliferating subependymal cells in the adult forebrain

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22487454

12 December 2020

based on heuristic

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Identifiers

10.1186/1756-6606-5-11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22487454%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Dimensions Publication ID

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/1756-6606-5-11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22487454%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22487454%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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