Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dep (Q42004459)

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scientific article published on July 2000

Language	Label	Description	Also known as
English	Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dep	scientific article published on July 2000

Statements

scholarly article

1 reference

Europe PubMed Central

15 October 2017

Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dep (English)

1 reference

Europe PubMed Central

15 October 2017

author name string

V A Nguyen

1

1 reference

Europe PubMed Central

15 October 2017

J Chen

2

1 reference

Europe PubMed Central

15 October 2017

F Hong

3

1 reference

Europe PubMed Central

15 October 2017

E J Ishac

4

1 reference

Europe PubMed Central

15 October 2017

B Gao

5

1 reference

Europe PubMed Central

15 October 2017

language of work or name

0 references

publication date

1 July 2000

1 reference

Europe PubMed Central

15 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

15 October 2017

349

1 reference

Europe PubMed Central

15 October 2017

427-434

1 reference

Europe PubMed Central

15 October 2017

Pt 2

1 reference

Europe PubMed Central

15 October 2017

Signaling pathways activated by interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Negative regulators of cytokine signal transduction

1 reference

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5 June 2018

Combination therapy for chronic hepatitis C: interferon and ribavirin

1 reference

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5 June 2018

The roles of amantadine, rimantadine, ursodeoxycholic acid, and NSAIDs, alone or in combination with alpha interferons, in the treatment of chronic hepatitis C.

1 reference

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5 June 2018

Combination therapy with interferon alfa and ribavirin as retreatment of interferon relapse in chronic hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Standards of treatment in chronic hepatitis C.

1 reference

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5 June 2018

Negative regulation of the JAK/STAT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Interferons in the management of viral hepatitis

1 reference

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5 June 2018

The CIS family: negative regulators of JAK-STAT signaling

1 reference

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5 June 2018

Activation of signal transducers and activators of transcription 1 and 3 by leukemia inhibitory factor, oncostatin-M, and interferon-gamma in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

How cells respond to interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Signal transduction in the interferon system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Effects of short and long term ethanol on the activation of signal transducer and activator transcription factor 3 in normal and regenerating liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Therapy of hepatitis C: consensus interferon trials. Consensus Interferon Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Therapy of hepatitis C: overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Transcriptional regulation of alpha(1b) adrenergic receptors (alpha(1b)AR) by nuclear factor 1 (NF1): a decline in the concentration of NF1 correlates with the downregulation of alpha(1b)AR gene expression in regenerating liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Interferon therapy for chronic hepatitis C in habitual drinkers: comparison with chronic hepatitis C in infrequent drinkers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Efficacy of interferon therapy in patients with chronic hepatitis C. Comparison between non-drinkers and drinkers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Gamma interferon induces rapid and coordinate activation of mitogen-activated protein kinase (extracellular signal-regulated kinase) and calcium-independent protein kinase C in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

5 June 2018

Cross-talk between alpha(1B)-adrenergic receptor (alpha(1B)AR) and interleukin-6 (IL-6) signaling pathways. Activation of alpha(1b)AR inhibits il-6-activated STAT3 in hepatic cells by a p42/44 mitogen-activated protein kinase-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

17 August 2018

Ethanol rapidly inhibits IL-6-activated STAT3 and C/EBP mRNA expression in freshly isolated rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

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Ethanol inhibits insulin-like growth factor-1-mediated signalling and proliferation of C6 rat glioblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221165

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Characterization of cytosolic calcium-activated phospholipid-dependent protein kinase activity in embryonal carcinoma cells. Effect of retinoc acid-induced differentiation of F9 cells to parietal endoderm

1 reference

https://pubmed.ncbi.nlm.nih.gov/10880341

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol causes desensitization of receptor-mediated phospholipase C activation in isolated hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10880341

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol impairs insulin receptor substrate-1 mediated signal transduction during rat liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/10880341

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10880341

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis C and alcohol

1 reference

https://pubmed.ncbi.nlm.nih.gov/10880341

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10880341

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3490427

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

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