Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases (Q42008598)

15 October 2017

Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases (English)

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15 October 2017

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Neupert W

1

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15 October 2017

Brugger R

2

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15 October 2017

Euchenhofer C

3

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15 October 2017

Brune K

4

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15 October 2017

Geisslinger G

5

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15 October 2017

language of work or name

English

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publication date

1 October 1997

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British Journal of Pharmacology

15 October 2017

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15 October 2017

122

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15 October 2017

3

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15 October 2017

487-492

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The suppression of granulocyte functions by lipophilic antioxidants

15 October 2017

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7 January 2021

A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors

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Isolation and characterization of rat liver microsomal R-ibuprofenoyl-CoA synthetase.

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The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences

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Variations in response to non-steroidal anti-inflammatory drugs

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Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence

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Effects of fatty acyl-coenzyme A esters on prostaglandin synthesis in rabbit kidney medulla microsomes

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Are there differences among nonsteroidal antiinflammatory drugs? Comparing acetylated salicylates, nonacetylated salicylates, and nonacetylated nonsteroidal antiinflammatory drugs

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7 January 2021

NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions

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Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase

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Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis

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Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs

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Cloning and expression of rat prostaglandin endoperoxide synthase (cyclooxygenase)-2 cDNA.

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Selective inhibition of cyclooxygenase 2

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An Algorithm for Least-Squares Estimation of Nonlinear Parameters

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Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice

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Is the formation of R-ibuprofenyl-adenylate the first stereoselective step of chiral inversion?

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Stereoselective high-performance liquid chromatographic determination of ketoprofen, ibuprofen and fenoprofen in plasma using a chiral alpha 1-acid glycoprotein column

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7 January 2021

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

1 reference

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Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostagl

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cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase

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2-Arylpropionyl-CoA epimerase: partial peptide sequences and tissue localization

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Molecular cloning and expression of a 2-arylpropionyl-coenzyme A epimerase: a key enzyme in the inversion metabolism of ibuprofen

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7 January 2021

Determination of the epimeric composition of ibuprofenyl-CoA

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7 January 2021

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

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Drug chirality: on the mechanism of R-aryl propionic acid class NSAIDs. Epimerization in humans and the clinical implications for the use of racemates

1 reference

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Enzymatic inversion at saturated carbon: nature and mechanism of the inversion of R(-) p-iso-butyl hydratropic acid

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7 January 2021

Enantiomers in arthritic disorders

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Human whole blood assays for inhibition of prostaglandin G/H synthases-1 and -2 using A23187 and lipopolysaccharide stimulation of thromboxane B2 production

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.BJP.0701415

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15 October 2017

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15 October 2017

PubMed publication ID

9351505

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