Synthesis and histamine H(3) and H(4) receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. (Q42015639)

15 October 2017

title

Synthesis and histamine H(3) and H(4) receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. (English)

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15 October 2017

Roland Geyer

1

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15 October 2017

Armin Buschauer

series ordinal

2

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15 October 2017

publication date

11 October 2011

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Archiv der Pharmazie - Chemistry in Life Sciences

15 October 2017

published in

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15 October 2017

volume

344

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15 October 2017

issue

12

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15 October 2017

page(s)

775-785

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Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes

15 October 2017

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The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation

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Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.

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The first potent and selective non-imidazole human histamine H4 receptor antagonists

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Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?

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Chiral NG-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity

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Acylguanidines as bioisosteres of guanidines: NG-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.

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21 January 2018

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21 January 2018

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A selective human H(4)-receptor agonist: (-)-2-cyano-1-methyl-3-[(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-y] methylguanidine

21 January 2018

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21 January 2018

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2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.

21 January 2018

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Oxidation of alcohols by “activated” dimethyl sulfoxide. a preparative, steric and mechanistic study

21 January 2018

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Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.

21 January 2018

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No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers

21 January 2018

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High constitutive activity and a G-protein-independent high-affinity state of the human histamine H(4)-receptor.

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ARDP.201100144

1 reference

15 October 2017

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