Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats (Q42018514)

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scientific article published on March 2011

Language	Label	Description	Also known as
English	Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats	scientific article published on March 2011

Statements

scholarly article

1 reference

Europe PubMed Central

15 October 2017

Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats (English)

1 reference

Europe PubMed Central

15 October 2017

1 reference

based on heuristic

inferred from title

diabetic nephropathy

1 reference

based on heuristic

inferred from title

author name string

Yoshihiro Kuno

1

1 reference

Europe PubMed Central

15 October 2017

Masayuki Iyoda

2

1 reference

Europe PubMed Central

15 October 2017

Takanori Shibata

3

1 reference

Europe PubMed Central

15 October 2017

Yuki Hirai

4

1 reference

Europe PubMed Central

15 October 2017

Tadao Akizawa

5

1 reference

Europe PubMed Central

15 October 2017

language of work or name

0 references

publication date

1 March 2011

1 reference

Europe PubMed Central

15 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

15 October 2017

162

1 reference

Europe PubMed Central

15 October 2017

1389-1400

1 reference

Europe PubMed Central

15 October 2017

6

1 reference

Europe PubMed Central

15 October 2017

Pretreatment of sildenafil attenuates ischemia-reperfusion renal injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

PDE-5 inhibition impedes TSP-1 expression, TGF-beta activation and matrix accumulation in experimental glomerulonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Phosphodiesterase type 5: expanding roles in cardiovascular regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

PDE5 inhibitors beyond erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Sildenafil citrate therapy for pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Role of nitric oxide in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Overview of phosphodiesterase 5 inhibition in erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Paradoxes of nitric oxide in the diabetic kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Does extracellular matrix expansion in glomerular disease require mesangial cell proliferation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

The glomerular response to injury: progression or resolution?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

OLETF (Otsuka Long-Evans Tokushima Fatty) rat: a new NIDDM rat strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

5 June 2018

Sildenafil attenuates renal ischemia reperfusion injury by decreasing leukocyte infiltration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

Sildenafil attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

The kidney expression of matrix metalloproteinase-9 in the diabetic nephropathy of Kkay mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

The antiproliferative effect of sildenafil on pulmonary artery smooth muscle cells is mediated via upregulation of mitogen-activated protein kinase phosphatase-1 and degradation of extracellular signal-regulated kinase 1/2 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

17beta-Estradiol supplementation reduces tubulointerstitial fibrosis by increasing MMP activity in the diabetic kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

Early treatment with cGMP phosphodiesterase inhibitor ameliorates progression of renal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

High concentration of glucose inhibits glomerular endothelial eNOS through a PKC mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

Decreased matrix degradation in diabetic nephropathy: effects of ACE inhibition on the expression and activities of matrix metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058170

17 August 2018

Reversal by L-arginine of a dysfunctional arginine/nitric oxide pathway in the endothelium of the genetic diabetic BB rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone mitigates renal glomerular vascular changes in high-fat, high-calorie-induced type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of High Glucose on Nitric Oxide Production and Endothelial Nitric Oxide Synthase Protein Expression in Human Glomerular Endothelial Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-arginine administration prevents glomerular hyperfiltration and decreases proteinuria in diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of endothelium-derived nitric oxide in the pathogenesis of the renal hemodynamic changes of experimental diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired nitric oxide release by glomeruli from diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A diabetogenic gene (ODB-1) assigned to the X-chromosome in OLETF rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cGMP-elevating agents suppress proliferation of vascular smooth muscle cells by inhibiting the activation of epidermal growth factor signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21133896

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.01149.X

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

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