Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700). (Q42024058)

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scientific article published on 14 September 2009

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English	Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700).	scientific article published on 14 September 2009

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scholarly article

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7 February 2020

Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700) (English)

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7 February 2020

Staphylococcus aureus

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inferred from title

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7 February 2020

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Jeffrey B Locke

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7 February 2020

Mark Hilgers

2

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7 February 2020

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14 September 2009

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7 February 2020

Antimicrobial Agents and Chemotherapy

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7 February 2020

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7 February 2020

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7 February 2020

5265-5274

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7 February 2020

Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance

1 reference

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Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci

1 reference

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5 June 2018

Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria

1 reference

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5 June 2018

Structural basis for cross-resistance to ribosomal PTC antibiotics

1 reference

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5 June 2018

In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains.

1 reference

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5 June 2018

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

1 reference

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R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance

1 reference

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Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

1 reference

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Update on macrolide-lincosamide-streptogramin, ketolide, and oxazolidinone resistance genes

1 reference

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Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents

1 reference

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5 June 2018

Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances

1 reference

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Microbial Selection

1 reference

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AM-7359--a novel oxazolidinone with low resistance potential and potent activity against drug resistant pathogens

1 reference

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Stepwise exposure of Staphylococcus aureus to pleuromutilins is associated with stepwise acquisition of mutations in rplC and minimally affects susceptibility to retapamulin

1 reference

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5 June 2018

First linezolid-resistant clinical isolates of Mycobacterium tuberculosis

1 reference

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5 June 2018

In vitro activity of the oxazolidinone RWJ-416457 against linezolid-resistant and -susceptible staphylococci and enterococci

1 reference

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5 June 2018

Biochemical characterization of the interactions of the novel pleuromutilin derivative retapamulin with bacterial ribosomes

1 reference

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5 June 2018

The Cfr rRNA methyltransferase confers resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A antibiotics

1 reference

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5 June 2018

Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

Single- and multistep resistance selection studies on the activity of retapamulin compared to other agents against Staphylococcus aureus and Streptococcus pyogenes

1 reference

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5 June 2018

Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus

1 reference

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5 June 2018

Enterococcus faecalis resistant to linezolid: case series and review of the literature

1 reference

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5 June 2018

In vitro activities of telithromycin, linezolid, and quinupristin-dalfopristin against Streptococcus pneumoniae with macrolide resistance due to ribosomal mutations

1 reference

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5 June 2018

Activity of AZD2563, a novel oxazolidinone, against Staphylococcus aureus strains with reduced susceptibility to vancomycin or linezolid

1 reference

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5 June 2018

Rapid detection and estimation by pyrosequencing of 23S rRNA genes with a single nucleotide polymorphism conferring linezolid resistance in Enterococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

Recombination Proficiency Influences Frequency and Locus of Mutational Resistance to Linezolid in Enterococcus faecalis

1 reference

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Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein l3.

1 reference

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5 June 2018

Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

Linezolid: its role in the treatment of gram-positive, drug-resistant bacterial infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

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High resolution structure of the large ribosomal subunit from a mesophilic eubacterium

1 reference

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5 June 2018

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

5 June 2018

Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions

1 reference

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5 June 2018

The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin

1 reference

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Evaluation of Alamar colorimetric broth microdilution susceptibility testing method for staphylococci and enterococci

1 reference

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In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis.

1 reference

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5 June 2018

In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents

1 reference

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Tiamulin resistance mutations in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

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Biochemical and genetic studies on two different types of erythromycin resistant mutants of Escherichia coli with altered ribosomal proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786364

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TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens

1 reference

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Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket

1 reference

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Endemic linezolid-resistant Staphylococcus epidermidis in a critical care unit

1 reference

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Linezolid and tiamulin cross-resistance in Staphylococcus aureus mediated by point mutations in the peptidyl transferase center

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19752277

12 December 2020

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