Characterization of squalene epoxidase of Saccharomyces cerevisiae by applying terbinafine-sensitive variants (Q42030684)

15 October 2017

Characterization of squalene epoxidase of Saccharomyces cerevisiae by applying terbinafine-sensitive variants (English)

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15 October 2017

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Saccharomyces cerevisiae

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Christoph Ruckenstuhl

1

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15 October 2017

Silvia Lang

2

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15 October 2017

Andrea Poschenel

3

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15 October 2017

Armin Eidenberger

4

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15 October 2017

Pravas Kumar Baral

5

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15 October 2017

Peter Kohút

6

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15 October 2017

Ivan Hapala

7

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15 October 2017

Karl Gruber

8

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15 October 2017

Friederike Turnowsky

9

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15 October 2017

language of work or name

English

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publication date

16 October 2006

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Antimicrobial Agents and Chemotherapy

15 October 2017

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15 October 2017

51

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15 October 2017

1

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15 October 2017

275-284

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describes a project that uses

15 October 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1797698/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A Phe389Leu substitution in ergA confers terbinafine resistance in Aspergillus fumigatus

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Biological, biochemical, and molecular characterization of a new clinical Trichophyton rubrum isolate resistant to terbinafine.

5 June 2018

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Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds

5 June 2018

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Candida glabrata erg1 mutant with increased sensitivity to azoles and to low oxygen tension

5 June 2018

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Molecular mechanism of terbinafine resistance in Saccharomyces cerevisiae

5 June 2018

1 reference

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Squalene epoxidase as hypocholesterolemic drug target revisited

5 June 2018

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A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae

5 June 2018

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GenTHREADER: an efficient and reliable protein fold recognition method for genomic sequences

5 June 2018

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Dual localization of squalene epoxidase, Erg1p, in yeast reflects a relationship between the endoplasmic reticulum and lipid particles

5 June 2018

1 reference

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Identification of a novel conserved sequence motif in flavoprotein hydroxylases with a putative dual function in FAD/NAD(P)H binding

5 June 2018

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Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.

5 June 2018

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Differential inhibition of fungal amd mammalian squalene epoxidases by the benzylamine SDZ SBA 586 in comparison with the allylamine terbinafine

5 June 2018

1 reference

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Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents

5 June 2018

1 reference

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ERG1, encoding squalene epoxidase, is located on the right arm of chromosome VII of Saccharomyces cerevisiae.

5 June 2018

1 reference

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Comparative protein modelling by satisfaction of spatial restraints

5 June 2018

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Recognition of errors in three-dimensional structures of proteins

5 June 2018

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Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure

5 June 2018

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Structure of a split yeast gene: complete nucleotide sequence of the actin gene in Saccharomyces cerevisiae

5 June 2018

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A comprehensive set of sequence analysis programs for the VAX

5 June 2018

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Prediction of the occurrence of the ADP-binding beta alpha beta-fold in proteins, using an amino acid sequence fingerprint

5 June 2018

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Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes

5 June 2018

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Crystal structure of the p-hydroxybenzoate hydroxylase-substrate complex refined at 1.9 A resolution. Analysis of the enzyme-substrate and enzyme-product complexes

5 June 2018

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NB-598: a potent competitive inhibitor of squalene epoxidase

5 June 2018

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Recovery of plasmids from yeast into Escherichia coli: shuttle vectors.

5 June 2018

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Getting started with yeast

5 June 2018

1 reference

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Squalene epoxidase as a target for the allylamines

5 June 2018

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The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization

5 June 2018

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Membrane raft lipid constituents affect drug susceptibilities of Candida albicans

5 June 2018

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Single amino acid exchanges in FAD-binding domains of squalene epoxidase of Saccharomyces cerevisiae lead to either loss of functionality or terbinafine sensitivity

17 August 2018

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Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis

17 August 2018

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Photoaffinity labeling identifies the substrate-binding site of mammalian squalene epoxidase

17 August 2018

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Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738.

17 August 2018

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Terbinafine resistance in a pleiotropic yeast mutant is caused by a single point mutation in the ERG1 gene

17 August 2018

1 reference

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Evidence for flavin movement in the function of p-hydroxybenzoate hydroxylase from studies of the mutant Arg220Lys.

17 August 2018

1 reference

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Photoaffinity labeling and site-directed mutagenesis of rat squalene epoxidase

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17043127

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.00988-06

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

17043127

1 reference