Analysis and pharmacological targeting of phospholipase C beta interactions with G proteins (Q42031592)

15 October 2017

Analysis and pharmacological targeting of phospholipase C beta interactions with G proteins (English)

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15 October 2017

David M Lehmann

1

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15 October 2017

Chujun Yuan

series ordinal

2

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15 October 2017

Alan V Smrcka

series ordinal

3

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15 October 2017

language of work or name

English

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publication date

1 January 2007

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15 October 2017

Methods in Enzymology

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15 October 2017

434

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15 October 2017

29-48

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Regulatory interactions between the amino terminus of G-protein betagamma subunits and the catalytic domain of phospholipase Cbeta2.

15 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Differential targeting of Gbetagamma-subunit signaling with small molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Structural and molecular characterization of a preferred protein interaction surface on G protein beta gamma subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Determination of the contact energies between a regulator of G protein signaling and G protein subunits and phospholipase C beta 1

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Site-specific, enzymatic biotinylation of recombinant proteins in Spodoptera frugiperda cells using biotin acceptor peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Regulation of phospholipase C isozymes by ras superfamily GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Crystal structure of Rac1 bound to its effector phospholipase C-β2

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Purification of Recombinant G Proteins from Sf9 Cells by Hexahistidine Tagging of Associated Subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Identification of a phospholipase C beta2 region that interacts with Gbeta-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Molecular cloning, splice variants, expression, and purification of phospholipase C-delta 4

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Development of an assay for phospholipase C using column-reconstituted, extruded phospholipid vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Regulation of phosphoinositide-specific phospholipase C

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https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Multiple forms of phosphoinositide-specific phospholipase C and different modes of activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Phospholipase C beta2 association with phospholipid interfaces assessed by fluorescence resonance energy transfer. G protein betagamma subunit-mediated translocation is not required for enzyme activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Membrane binding of phospholipases C-beta 1 and C-beta 2 is independent of phosphatidylinositol 4,5-bisphosphate and the alpha and beta gamma subunits of G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Identification of a structural element in phospholipase C beta2 that interacts with G protein betagamma subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Evidence that a protein-protein interaction 'hot spot' on heterotrimeric G protein betagamma subunits is used for recognition of a subclass of effectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Two alpha subunits of the Gq class of G proteins stimulate phosphoinositide phospholipase C-beta 1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

The pleckstrin homology domain of phospholipase C-beta(2) links the binding of gbetagamma to activation of the catalytic core

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934003-2

7 January 2021

10.1016/S0076-6879(07)34003-2

Identifiers

DOI

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15 October 2017

1 reference