Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase (Q42032140)

15 October 2017

Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase (English)

1 reference

Soluble epoxide hydrolase

15 October 2017

0 references

author name string

Paul D Jones

1

1 reference

15 October 2017

Hsing-Ju Tsai

2

1 reference

15 October 2017

Zung N Do

3

1 reference

15 October 2017

Christophe Morisseau

4

1 reference

15 October 2017

Bruce D Hammock

5

1 reference

15 October 2017

language of work or name

English

0 references

publication date

25 July 2006

1 reference

Bioorganic & Medicinal Chemistry Letters

15 October 2017

1 reference

15 October 2017

16

1 reference

15 October 2017

19

1 reference

15 October 2017

5212-5216

1 reference

An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Molecular properties that influence the oral bioavailability of drug candidates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Potent urea and carbamate inhibitors of soluble epoxide hydrolases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

VMD: visual molecular dynamics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Design and synthesis of orally active benzamide derivatives as potent serotonin 4 receptor agonist

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904344

Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16870439

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16870439

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2006.07.009

1 reference

15 October 2017

1 reference

15 October 2017

1 reference