Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control. (Q42036369)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235227%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control (English)

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1 January 2020

2

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1 January 2020

Hisashi Tatebe

3

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1 January 2020

Kazuhiro Shiozaki

5

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1 January 2020

author name string

Kyoko Ikeda

1

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1 January 2020

Fuyuhiko Tamanoi

4

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1 January 2020

language of work or name

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1 November 2007

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1 January 2020

number of pages

7

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inferred from page(s)

published in

Cell Cycle

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1 January 2020

volume

7

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1 January 2020

issue

3

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1 January 2020

page(s)

358-364

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The TSC/Rheb/TOR signaling pathway in fission yeast and mammalian cells: temperature sensitive and constitutive active mutants of TOR.

1 January 2020

cites work

1 reference

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TOR signaling and S6 kinase 1: Yeast catches up.

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Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

5 June 2018

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Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast.

5 June 2018

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Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity

5 June 2018

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

5 June 2018

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5 June 2018

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TOR signaling in growth and metabolism

5 June 2018

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TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium

5 June 2018

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Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization

5 June 2018

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Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation

5 June 2018

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Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase

5 June 2018

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The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins

5 June 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

5 June 2018

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The evolution of the Sin1 gene product, a little known protein implicated in stress responses and type I interferon signaling in vertebrates

5 June 2018

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The forkhead transcription factor Fkh2 regulates the cell division cycle of Schizosaccharomyces pombe.

5 June 2018

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5 June 2018

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Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase

5 June 2018

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Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases

5 June 2018

1 reference

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Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae

5 June 2018

1 reference

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Global transcriptional responses of fission yeast to environmental stress

5 June 2018

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Role of Akt/protein kinase B in metabolism.

5 June 2018

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Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

5 June 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

5 June 2018

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Distinct regulatory proteins control the graded transcriptional response to increasing H(2)O(2) levels in fission yeast Schizosaccharomyces pombe.

5 June 2018

1 reference

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PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

5 June 2018

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

5 June 2018

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Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway.

5 June 2018

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Direct control of the Forkhead transcription factor AFX by protein kinase B

5 June 2018

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Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe

5 June 2018

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Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe

5 June 2018

1 reference

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Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

An osmosensing signal transduction pathway in yeast.

5 June 2018

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sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

cdc25+ functions as an inducer in the mitotic control of fission yeast

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

5 June 2018

1 reference

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Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae

5 June 2018

1 reference

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Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast

5 June 2018

1 reference

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Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

Characterisation of two novel fork-head gene homologues of Schizosaccharomyces pombe: their involvement in cell cycle and sexual differentiation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

Fission yeast tor1 functions in response to various stresses including nitrogen starvation, high osmolarity, and high temperature

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274895

Gene ste20 controls amiloride sensitivity and fertility in Schizosaccharomyces pombe.

17 August 2018

1 reference

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S. pombe sck2+, a second homologue of S. cerevisiae SCH9 in fission yeast, encodes a putative protein kinase closely related to PKA in function.

17 August 2018

1 reference

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Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast

17 August 2018

1 reference

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Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene

17 August 2018

1 reference

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Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast

17 August 2018

1 reference

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Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.

17 August 2018

1 reference

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Regulated mRNA stability of the Cdk inhibitor Rum1 links nutrient status to cell cycle progression

17 August 2018

1 reference

12 December 2020

Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast

1 reference

12 December 2020

The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast

1 reference

12 December 2020

Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation

1 reference

12 December 2020

Identifiers

DOI

10.4161/CC.7.3.5245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235227%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18235227%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

18235227

1 reference