Cholesterol as treatment for pneumococcal keratitis: cholesterol-specific inhibition of pneumolysin in the cornea (Q42045480)

15 October 2017

Cholesterol as treatment for pneumococcal keratitis: cholesterol-specific inhibition of pneumolysin in the cornea (English)

1 reference

15 October 2017

Mary E Marquart

1

1 reference

15 October 2017

Kathryn S Monds

2

1 reference

15 October 2017

Clare C McCormick

3

1 reference

15 October 2017

Sherrina N Dixon

4

1 reference

15 October 2017

Melissa E Sanders

5

1 reference

15 October 2017

Julian M Reed

6

1 reference

15 October 2017

Larry S McDaniel

7

1 reference

15 October 2017

Armando R Caballero

8

1 reference

15 October 2017

Richard J O'Callaghan

9

1 reference

15 October 2017

language of work or name

English

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publication date

1 June 2007

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Investigative Ophthalmology Visual Science

15 October 2017

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15 October 2017

48

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15 October 2017

6

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15 October 2017

2661-2666

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THP-1 monocytes up-regulate intercellular adhesion molecule 1 in response to pneumolysin from Streptococcus pneumoniae

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Pneumolysin-dependent and -independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by Streptococcus pneumoniae

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Bacterial keratitis: a prospective clinical and microbiological study

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Essential role of domain 4 of pneumolysin from Streptococcus pneumoniae in cytolytic activity as determined by truncated proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Structural analysis of the protein/lipid complexes associated with pore formation by the bacterial toxin pneumolysin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Epidemiology and aetiological diagnosis of corneal ulceration in Madurai, south India

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Pneumolysin: a multifunctional pneumococcal virulence factor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Penicillin-resistant Streptococcus pneumoniae keratitis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Causes of suppurative keratitis in Ghana

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Microbial keratitis in children

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Spectrum of microbial keratitis in South Florida.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Binding of cholesterol by sulfhydryl-activated cytolysins.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Activation of human complement by the pneumococcal toxin pneumolysin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Microbiological diagnosis of suppurative keratitis in Bangladesh

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Epidemiologic characteristics, predisposing factors, and etiologic diagnosis of corneal ulceration in Nepal

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Structure and function of pneumolysin, the multifunctional, thiol-activated toxin of Streptococcus pneumoniae

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Streptococcus pneumoniae endophthalmitis: a study of 36 cases with special reference to antibiotic resistance and treatment options.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Pneumococcal keratitis: a clinical profile

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Microbial keratitis in children

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Survey of mycotic and bacterial keratitis in Sri Lanka.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Suppurative corneal ulceration in Bangladesh. A study of 142 cases examining the microbiological diagnosis, clinical and epidemiological features of bacterial and fungal keratitis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814300

Structure and molecular mechanism of a functional form of pneumolysin: a cholesterol-dependent cytolysin from Streptococcus pneumoniae

1 December 2018

1 reference

12 December 2020

Confirmation of the role of pneumolysin in ocular infections with Streptococcus pneumoniae

1 reference

12 December 2020

High expression of chemokines Gro-alpha (CXCL-1), IL-8 (CXCL-8), and MCP-1 (CCL-2) in inflamed human corneas in vivo

1 reference

12 December 2020

Microbial keratitis in childhood

1 reference

12 December 2020

Growth and virulence of a complement-activation-negative mutant of Streptococcus pneumoniae in the rabbit cornea

1 reference

12 December 2020

Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia

1 reference

12 December 2020

Corneal ulcers in two institutions in Singapore: analysis of causative factors, organisms and antibiotic resistance

1 reference

12 December 2020

Streptococcus pneumoniae produces a second haemolysin that is distinct from pneumolysin

1 reference

12 December 2020

Streptolysin O: a proposed model of allosteric interaction between a pore-forming protein and its target lipid bilayer

1 reference

12 December 2020

Ocular toxin of the pneumococcus

1 reference

12 December 2020

1 reference

12 December 2020

Epidemiology of microbial keratitis in southern California. A multivariate analysis

1 reference

12 December 2020

Factors influencing predilection and outcome in bacterial keratitis

1 reference

12 December 2020

The role of pneumolysin in ocular infections with Streptococcus pneumoniae

1 reference

12 December 2020

Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.07-0017

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

17525197

1 reference