The role of p53 in bleomycin-induced DNA damage in the lung. A comparative study with the small intestine (Q42048854)

15 October 2017

The role of p53 in bleomycin-induced DNA damage in the lung. A comparative study with the small intestine (English)

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15 October 2017

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K Okudela

1

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15 October 2017

T Ito

2

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15 October 2017

H Mitsui

3

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15 October 2017

H Hayashi

4

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15 October 2017

N Udaka

5

1 reference

15 October 2017

M Kanisawa

6

1 reference

15 October 2017

H Kitamura

7

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15 October 2017

language of work or name

English

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publication date

1 October 1999

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The American Journal of Pathology

15 October 2017

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15 October 2017

155

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15 October 2017

4

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15 October 2017

1341-1351

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A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB.

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: apoptosis and cell cycle arrest.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Inhibition of TNF-alpha-induced NF-kappaB activation and IL-8 release in A549 cells with the proteasome inhibitor MG-132.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

The potential role of BAX and BCL-2 expression in diffuse alveolar damage

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Analysis of p21Waf1/Cip1 expression in normal, premalignant, and malignant cells during the development of human lung adenocarcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

The p53 response to ionising radiation in adult and developing murine tissues.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

C-C chemokines: novel mediators of the profibrotic inflammatory response to bleomycin challenge

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Three distinct signalling responses by murine fibroblasts to genotoxic stress

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

NF-kappa B: ten years after

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

WAF1, a potential mediator of p53 tumor suppression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Growth factor modulation of p53-mediated growth arrest versus apoptosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Cellular localization of transforming growth factor-beta expression in bleomycin-induced pulmonary fibrosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Pulmonary platelet trapping induced by bleomycin: correlation with fibrosis and involvement of the beta 2 integrins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Studies on the cytotoxicity of bleomycin in the small intestine of the mouse

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Analysis of DNA synthesis in herpes simplex virus infected cells by dual parameter flow cytometry

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Murine Strain Differences in Acute Lung Injury and Activation of Poly(ADP-ribose) Polymerase by In Vitro Exposure of Lung Slices to Bleomycin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Bleomycin-induced pulmonary fibrosis in the rat: inhibition by indomethacin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

Oxygen toxicity in mouse lung: pathways to cell death.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867000

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

17 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Lung interleukin-5 expression in murine bleomycin-induced pulmonary fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Increased expression of transforming growth factor beta isoforms (beta 1, beta 2, beta 3) in bleomycin-induced pulmonary fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

p53, mutation frequency and apoptosis in the murine small intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Ki-67 (MIB 5) immunostaining of mouse lung tumors induced by 4-nitroquinoline 1-oxide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Demonstration of DNA damage/repair in individual cells using in situ end labelling: association of p53 with sites of DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Measurement of the kinetics of DNA repair synthesis after uv irradiation using immunochemical staining of incorporated 5-bromo-2'-deoxyuridine and flow cytometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965236-4

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67

7 January 2021

1 reference

12 December 2020

Acute pulmonary toxicity of bleomycin: DNA scission and matrix protein mRNA levels in bleomycin-sensitive and -resistant strains of mice

1 reference

12 December 2020

High levels of p53 protein in UV-irradiated normal human skin

1 reference

12 December 2020

Effects of ionizing irradiation and beta-adrenergic stimulation on gene expression pattern in rat submandibular glands

1 reference

12 December 2020

P53 and p21 (Waf1/Cip1) mRNA expression associated with DNA damage and repair in acute immune complex alveolitis in mice

1 reference

12 December 2020

10.1016/S0002-9440(10)65236-4

Identifiers

DOI

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

10514416

1 reference