Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. (Q42049241)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9502421%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1 (English)

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10 November 2019

1 reference

Miyazawa K

1

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10 November 2019

Mori A

series ordinal

2

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10 November 2019

Yamamoto K

series ordinal

3

1 reference

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10 November 2019

Okudaira H

series ordinal

4

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10 November 2019

language of work or name

English

0 references

publication date

1 March 1998

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The American Journal of Pathology

10 November 2019

published in

1 reference

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10 November 2019

volume

152

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10 November 2019

issue

3

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10 November 2019

page(s)

793-803

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The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression

10 November 2019

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Role of cytokines in rheumatoid arthritis

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene

5 June 2018

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5 June 2018

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Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human

5 June 2018

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B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes

5 June 2018

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Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells

5 June 2018

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5 June 2018

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Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids

5 June 2018

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5 June 2018

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A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif

5 June 2018

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A multiple cytokine- and second messenger-responsive element in the enhancer of the human interleukin-6 gene: similarities with c-fos gene regulation

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence

5 June 2018

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Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene

5 June 2018

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Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts

5 June 2018

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The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B

5 June 2018

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Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative

5 June 2018

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Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes

5 June 2018

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Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

5 June 2018

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The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis

5 June 2018

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The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression

5 June 2018

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5 June 2018

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17 August 2018

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1 December 2018

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12 December 2020

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12 December 2020

IL-6 functions as an exocrine hormone in inflammation. Hepatocytes undergoing acute phase responses require exogenous IL-6

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Interleukin 6 levels in synovial fluids of patients with different arthritides: correlation with local IgM rheumatoid factor and systemic acute phase protein production

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Treatment of severe rheumatoid arthritis by anti-interleukin 6 monoclonal antibody

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Elevated cytokine levels in synovial fluid of rheumatoid arthritis correlates with the presence of cytomegalovirus genome

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Interleukin-6 (IL-6) induces the proliferation of synovial fibroblastic cells in the presence of soluble IL-6 receptor

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Regulation of interleukin-6 gene expression by steroids

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12 December 2020

Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65

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Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

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Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines

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Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma

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Synergism between interleukin-6 and interleukin-3 in supporting proliferation of human hematopoietic stem cells: comparison with interleukin-1 alpha

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Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

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Interleukin 4 is at 5q31 and interleukin 6 is at 7p15

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Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

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Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9502421%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

9502421

1 reference