MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver (Q42053609)

15 October 2017

MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver (English)

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15 October 2017

M G Belinsky

1

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15 October 2017

G D Kruh

series ordinal

2

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15 October 2017

language of work or name

English

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publication date

1 July 1999

1 reference

British Journal of Cancer

15 October 2017

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15 October 2017

80

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15 October 2017

9

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15 October 2017

1342-1349

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690527

15 October 2017

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ARA, a novel ABC transporter, is located at 16p13.1, is deleted in inv(16) leukemias, and is shown to be expressed in primitive hematopoietic precursors

5 June 2018

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Amplification and expression of the ABC transporters ARA and MRP in a series of multidrug-resistant leukaemia cell sublines

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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

5 June 2018

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Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver

5 June 2018

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A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells

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Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

5 June 2018

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Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines

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Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

5 June 2018

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The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

5 June 2018

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Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database

5 June 2018

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A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation

5 June 2018

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cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

5 June 2018

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Membrane topology and glycosylation of the human multidrug resistance-associated protein

5 June 2018

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The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump

5 June 2018

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ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

5 June 2018

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Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

5 June 2018

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Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene.

5 June 2018

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Prediction of transmembrane segments in proteins utilising multiple sequence alignments

5 June 2018

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Biochemistry of multidrug resistance mediated by the multidrug transporter

5 June 2018

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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

5 June 2018

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Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells

5 June 2018

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

5 June 2018

1 reference

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Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

5 June 2018

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Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution.

5 June 2018

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Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363063

The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene

5 June 2018

1 reference

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363063

ABC Transporters: From Microorganisms to Man

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363063

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363063

The multidrug resistance-associated protein (MRP) subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363063

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363063

Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats

17 August 2018

1 reference

12 December 2020

Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence

1 reference

12 December 2020

Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion

1 reference

12 December 2020

Hepatic, intestinal and renal transport of 1-naphthol-beta-D-glucuronide in mutant rats with hereditary-conjugated hyperbilirubinemia

1 reference

12 December 2020

Expression pattern of MRP in human tissues and adult solid tumor cell lines

1 reference

12 December 2020

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6690527

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Dimensions Publication ID

15 October 2017

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1 reference

15 October 2017

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