X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative. (Q42059054)

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scientific article published on December 2006

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English	X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative.	scientific article published on December 2006

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17145714%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative (English)

1 reference

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22 December 2019

3

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22 December 2019

Christine J. Cardin

4

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22 December 2019

author name string

Nicholas H Hopcroft

1

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22 December 2019

Anna L Brogden

2

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22 December 2019

publication date

1 December 2006

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22 December 2019

Nucleic Acids Research

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22 December 2019

34

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22 December 2019

22

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22 December 2019

6663-6672

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22 December 2019

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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

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Structural characterisation of bisintercalation in higher-order DNA at a junction-like quadruplex

1 reference

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Substructure solution with SHELXD

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1H NMR study of the binding of Bis(acridines) to d(AT)5.d(AT)5. 1. Mode of binding

1 reference

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5 June 2018

Crystal structure of 9-amino-N-[2-(4-morpholinyl)ethyl]-4-acridinecarboxamide bound to d(CGTACG)2: implications for structure-activity relationships of acridinecarboxamide topoisomerase poisons

1 reference

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Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions

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1 reference

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Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms

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Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides

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Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing

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5 June 2018

Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2

1 reference

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5 June 2018

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution

1 reference

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Structure of a DNA-bisdaunomycin complex

1 reference

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5 June 2018

DNA distortion in bis-intercalated complexes

1 reference

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A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment

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Bisintercalators of DNA with a rigid linker in an extended configuration

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5 June 2018

Evidence for cross-linking DNA by bis-intercalators with rigid and extended linkers is provided by knotting and catenation

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Topoisomerase I/II selectivity among derivatives of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA).

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Potential antitumor agents. 43. Synthesis and biological activity of dibasic 9-aminoacridine-4-carboxamides, a new class of antitumor agent

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1 reference

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Effects of ring substituents and linker chains on the bifunctional intercalation of diacridines into deoxyribonucleic acid

1 reference

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12 December 2020

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Identifiers

10.1093/NAR/GKL930

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22 December 2019

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22 December 2019

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22 December 2019

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