Role of hydrogen peroxide in the cytotoxicity of the xanthine/xanthine oxidase system (Q42059743)

15 October 2017

Role of hydrogen peroxide in the cytotoxicity of the xanthine/xanthine oxidase system (English)

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15 October 2017

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Link EM

1

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PMCID

1148716

15 October 2017

Riley PA

series ordinal

2

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PMCID

1148716

15 October 2017

language of work or name

English

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publication date

1 January 1988

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15 October 2017

9

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inferred from page(s)

published in

Biochemical Journal

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15 October 2017

249

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15 October 2017

391-399

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15 October 2017

2

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Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Cell killing and DNA damage by hydrogen peroxide are mediated by intracellular iron.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Uric acid: functions and determination

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Free-radical mechanisms in tissue injury

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Oxygen toxicity, oxygen radicals, transition metals and disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

The Role of Active Oxygen (102 and 0·2-) Induced by Crude Coal Tar and Its Ingredients Used in Photochemotheraphy of Skin Diseases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

The kinetics of degradation of DNA and RNA by H2O2

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Chemical analysis of DNA alterations. I. Base liberation and backbone breakage of DNA and oligodeoxyadenylic acid induced by hydrogen peroxide and hydroxylamine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

The reaction of xanthine oxidase with molecular oxygen.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Kinetic studies on the substrate reduction of xanthine oxidase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Oxidants increase paracellular permeability in a cultured epithelial cell line

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Oxidation of cell wall polysaccharides by hydrogen peroxide: a potential mechanism for cell wall breakdown in plants

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Formation of hydroxyl radicals in the presence of ferritin and haemosiderin. Is haemosiderin formation a biological protective mechanism?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Mammalian cells are not killed by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Radiation and hydrogen peroxide induced free radical damage to DNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

5 June 2018

Superoxide dismutases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

The mechanism of liver microsomal lipid peroxidation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Singlet oxygen production associated with enzyme-catalyzed lipid peroxidation in liver microsomes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

A possible mechanism of the generation of singlet molecular oxygen in NADPH-dependent microsomal lipid peroxidation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Equilibrium properties of xanthine oxidase containing FAD analogs of varying oxidation-reduction potential.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148716

Evidence that peroxidation of lysosomal membranes is initiated by hydroxyl free radicals produced during flavin enzyme activity

17 August 2018

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12 December 2020

The microestimation of succinate and the extinction coefficient of cytochrome c

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12 December 2020

The mechanism of action of xanthine oxidase

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12 December 2020

Estimation of Life Times and Diffusion Distances of Radicals Involved in X-Ray-Induced DNA Strand Breaks or Killing of Mammalian Cells

1 reference

12 December 2020

Hydrogen peroxide causes the fatal injury to human fibroblasts exposed to oxygen radicals

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12 December 2020

The reaction of reduced xanthine oxidase with oxygen. Kinetics of peroxide and superoxide formation

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12 December 2020

Studies on the oxidative half-reaction of xanthine oxidase

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12 December 2020

A study of the reactivity of HO2/O2- with unsaturated fatty acids

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12 December 2020

Formation of hydroxyl radicals from hydrogen peroxide and iron salts by superoxide- and ascorbate-dependent mechanisms: relevance to the pathology of rheumatoid disease

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12 December 2020

Macrophage mediated damage to rat lenses in culture: a possible model for uveitis-associated cataract

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12 December 2020

Copper salt-dependent hydroxyl radical formation. Damage to proteins acting as antioxidants

1 reference

12 December 2020

Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

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12 December 2020

The role of oxygen free radicals in human disease processes

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12 December 2020

Redox cycling and lipid peroxidation: the central role of iron chelates

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12 December 2020

Mechanisms of the killing of cultured hepatocytes by hydrogen peroxide

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12 December 2020

In vivo formation of single-strand breaks in DNA by hydrogen peroxide is mediated by the Haber-Weiss reaction

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12 December 2020

Correlation between cytotoxic effect of hydrogen peroxide and the yield of DNA strand breaks in cells of different species

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12 December 2020

Formation of long-lived hydroxyl free radical adducts of proline and hydroxyproline in a fenton reaction

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12 December 2020

Hydroxyl free radical reactions with amino acids and proteins studied by electron spin resonance spectroscopy and spin-trapping

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12 December 2020

Endogenous defenses against the cytotoxicity of hydrogen peroxide in cultured rat hepatocytes

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12 December 2020

Superoxide dismutase inhibits the superoxide-driven Fenton reaction at two different levels. Implications for a wider protective role

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12 December 2020

The effects of "oxygen radicals" generated in the medium on lenses in organ culture: inhibition of damage by chelated iron

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12 December 2020

Substrate-induced chemiluminescence of xanthine oxidase and aldehyde oxidase

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12 December 2020

The role of superoxide and singlet oxygen in lipid peroxidation promoted by xanthine oxidase

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12 December 2020

Identifiers

DOI

10.1042/BJ2490391

1 reference

15 October 2017

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15 October 2017

1 reference

PMCID

1148716