Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide. (Q42059881)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17070840%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide (English)

1 reference

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21 December 2019

0 references

1

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21 December 2019

author name string

Yuka Okabe

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17070840%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Eng-Hui Yap

series ordinal

3

1 reference

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21 December 2019

Teresa Head-Gordon

series ordinal

4

1 reference

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21 December 2019

language of work or name

English

0 references

publication date

7 October 2006

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Journal of Molecular Biology

21 December 2019

published in

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21 December 2019

volume

365

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21 December 2019

issue

2

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21 December 2019

page(s)

535-550

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Amyloid beta-protein monomer structure: a computational and experimental study.

21 December 2019

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The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding

5 June 2018

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Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

5 June 2018

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3D structure of Alzheimer's amyloid-beta(1-42) fibrils

5 June 2018

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Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

5 June 2018

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Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.

5 June 2018

1 reference

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On the nucleation of amyloid beta-protein monomer folding

5 June 2018

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Influence of denatured and intermediate states of folding on protein aggregation

5 June 2018

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Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

5 June 2018

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In silico study of amyloid beta-protein folding and oligomerization

5 June 2018

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Aqueous urea solution destabilizes Abeta(16-22) oligomers

5 June 2018

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Molecular dynamics simulation of amyloid beta dimer formation

5 June 2018

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Oligomerization of amyloid Abeta16-22 peptides using hydrogen bonds and hydrophobicity forces

5 June 2018

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Intermediates and the folding of proteins L and G.

5 June 2018

1 reference

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Principles of protein folding, misfolding and aggregation

5 June 2018

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Therapeutic approaches to protein-misfolding diseases

5 June 2018

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Protein folding and misfolding

5 June 2018

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Coarse-grained sequences for protein folding and design

5 June 2018

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

5 June 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

5 June 2018

1 reference

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A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

5 June 2018

1 reference

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Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain

5 June 2018

1 reference

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Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

5 June 2018

1 reference

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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

5 June 2018

1 reference

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Matching simulation and experiment: a new simplified model for simulating protein folding

5 June 2018

1 reference

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Redesigning the hydrophobic core of a model beta-sheet protein: destabilizing traps through a threading approach

5 June 2018

1 reference

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Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

5 June 2018

1 reference

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Kinetic theory of fibrillogenesis of amyloid beta-protein

5 June 2018

1 reference

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On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

5 June 2018

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

5 June 2018

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beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

5 June 2018

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The molecular pathology of Alzheimer's disease

5 June 2018

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Structure of the 21-30 fragment of amyloid beta-protein.

5 June 2018

1 reference

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Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.

17 August 2018

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Direct observation of Abeta amyloid fibril growth and inhibition

17 August 2018

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Dissecting the assembly of Abeta16-22 amyloid peptides into antiparallel beta sheets.

17 August 2018

1 reference

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Protein engineering study of protein L by simulation

17 August 2018

1 reference

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Analysis of protein aggregation kinetics.

17 August 2018

1 reference

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Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674024

Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674024

Control of Amyloid β-Peptide Protofibril Formation by a Designed Template Assembly

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674024

10.1016/J.JMB.2006.10.011

1 December 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17070840%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17070840%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

17070840

1 reference