Tryprostatin A, a specific and novel inhibitor of microtubule assembly (Q42061827)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9677311%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Tryprostatin A, a specific and novel inhibitor of microtubule assembly (English)

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13 November 2019

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ChEBI release 2020-05-28

1

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13 November 2019

author name string

M Kondoh

2

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13 November 2019

C B Cui

3

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13 November 2019

T Mayumi

4

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13 November 2019

H Osada

5

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13 November 2019

language of work or name

English

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publication date

1 August 1998

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13 November 2019

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13 November 2019

volume

333 ( Pt 3)

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13 November 2019

page(s)

543-548

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Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly

13 November 2019

cites work

1 reference

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Screening of cell cycle inhibitors from microbial metabolites by a bioassay using a mouse cdc2 mutant cell line, tsFT210.

5 June 2018

1 reference

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Tubulin-colchicine complex inhibits microtubule elongation at both plus and minus ends.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Microtubule Assembly in the Absence of Added Nucleotides

5 June 2018

1 reference

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Tubulin subunit carboxyl termini determine polymerization efficiency

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Tubulin, hybrid dimers, and tubulin S. Stepwise charge reduction and polymerization

5 June 2018

1 reference

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Studies on macrocyclic lactone antibiotics. XI. Anti-mitotic and anti-tubulin activity of new antitumor antibiotics, rhizoxin and its homologues

5 June 2018

1 reference

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Antiinvasive activity of estramustine on malignant MO4 mouse cells and on DU-145 human prostate carcinoma cells in vitro.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

The primary structure and heterogeneity of tau protein from mouse brain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Rhizoxin binding to tubulin at the maytansine-binding site

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Effects of antimitotic agents on tubulin-nucleotide interactions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Bis-ANS as a specific inhibitor for microtubule-associated protein induced assembly of tubulin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Estramustine-phosphate binds to a tubulin binding domain on microtubule-associated proteins MAP-2 and tau.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Phase II study of estramustine and vinblastine, two microtubule inhibitors, in hormone-refractory prostate cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

A protein factor essential for microtubule assembly

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Binding of maytansine to rat brain tubulin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Action of the vinca alkaloids vincristine, vinblastine, and desacetyl vinblastine amide on microtubules in vitro

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Maytansine binding to the vinblastine sites of tubulin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

The reconstitution of microtubules from purified calf brain tubulin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

In vitro reconstitution of calf brain microtubules: effects of macromolecules

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Fractionation of brain microtubule-associated proteins. Isolation of two different proteins which stimulate tubulin polymerization in vitro

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Promotion of microtubule assembly in vitro by taxol

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Rat cell line 3y1 and its virogenic polyoma- and SV40-transformed derivatives

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. I. Taxonomy, fermentation, isolation and biological properties.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Paclitaxel plus estramustine in metastatic hormone-refractory prostate cancer.

17 August 2018

1 reference

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Bis(1,8-anilinonaphthalenesulfonate). A novel and potent inhibitor of microtubule assembly

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Separation of active tubulin and microtubule-associated proteins by ultracentrifugation and isolation of a component causing the formation of microtubule bundles

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219615

Interaction of estramustine with tubulin isotypes

17 August 2018

1 reference

12 December 2020

The colchicine-binding and pyrene-excimer-formation activities of tubulin involve a common cysteine residue in the beta subunit

1 reference

12 December 2020

Isolation and analysis of a mammalian temperature-sensitive mutant defective in G2 functions

1 reference

12 December 2020

Effect of estramustine phosphate on the assembly of trypsin-treated microtubules and microtubules reconstituted from purified tubulin with either tau, MAP2, or the tubulin-binding fragment of MAP2

1 reference

12 December 2020

Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, a potent inhibitor of protein kinases

1 reference

12 December 2020

Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines

1 reference

12 December 2020

Estramustine depolymerizes microtubules by binding to tubulin

1 reference

12 December 2020

Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus

1 reference

12 December 2020

Identification of cysteine 354 of beta-tubulin as part of the binding site for the A ring of colchicine

1 reference

12 December 2020

Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures

1 reference

12 December 2020

Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ3330543

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9677311%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9677311%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PubMed publication ID

9677311

1 reference