Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. (Q42062389)

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25 January 2020

title

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy (English)

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25 January 2020

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4

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25 January 2020

Damian J. Tyler

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8

George K Radda

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25 January 2020

author name string

Marie A Schroeder

1

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25 January 2020

Helen J Atherton

2

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25 January 2020

Daniel R Ball

3

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25 January 2020

Lisa C Heather

5

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25 January 2020

Julian L Griffin

6

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25 January 2020

Kieran Clarke

7

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language of work or name

English

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publication date

27 March 2009

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25 January 2020

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25 January 2020

volume

23

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issue

8

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25 January 2020

page(s)

2529-2538

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Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle

25 January 2020

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In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

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Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

5 June 2018

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Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.

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5 June 2018

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The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

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Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

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Pyruvate dehydrogenase and the regulation of glucose oxidation in hypertrophied rat hearts

5 June 2018

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5 June 2018

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Citrate as an in vivo marker to discriminate prostate cancer from benign prostatic hyperplasia and normal prostate peripheral zone: detection via localized proton spectroscopy

5 June 2018

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The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme

5 June 2018

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Quantitation of the efflux of acylcarnitines from rat heart, brain, and liver mitochondria.

5 June 2018

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Carbon flux through citric acid cycle pathways in perfused heart by 13C NMR spectroscopy.

5 June 2018

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Contribution of exogenous substrates to acetyl coenzyme A: measurement by 13C NMR under non-steady-state conditions

5 June 2018

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Metabolic responses to cardiac hypoxia. Increased production of succinate by rabbit papillary muscles

5 June 2018

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Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a

5 June 2018

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Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

5 June 2018

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Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-initial experience

17 August 2018

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A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-alpha null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome.

17 August 2018

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Extracellular volume and transsarcolemmal proton movement during ischemia and reperfusion: a 31P NMR spectroscopic study of the isovolumic rat heart

17 August 2018

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12 December 2020

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12 December 2020

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12 December 2020

Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate?

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12 December 2020

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12 December 2020

Citrate as an Intermediary in the Inhibition of Phosphofructokinase in Rat Heart Muscle by Fatty Acids, Ketone Bodies, Pyruvate, Diabetes and Starvation

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12 December 2020

Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis

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12 December 2020

Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts

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12 December 2020

Studies of metabolism in the isolated, perfused rat heart using 13 C NMR

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Role of glycolytic products in damage to ischemic myocardium. Dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts

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A 1H-NMR study of the activity expressed by lactate dehydrogenase in the human erythrocyte

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Energy metabolism and contractile function in rat heart during graded, isovolumic perfusion using 31P nuclear magnetic resonance spectroscopy

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Mechanisms of substrate preference for oxidative metabolism during early myocardial reperfusion

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12 December 2020

Nonglucose substrates increase glycogen synthesis in vivo in dog heart

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12 December 2020

Identifiers

DOI

10.1096/FJ.09-129171

1 reference

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25 January 2020

1 reference

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25 January 2020

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